Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review

Pyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatme...

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Main Authors: Gordon W Jung, Michael D Parkins, Deirdre Church
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2009/971735
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author Gordon W Jung
Michael D Parkins
Deirdre Church
author_facet Gordon W Jung
Michael D Parkins
Deirdre Church
author_sort Gordon W Jung
collection DOAJ
description Pyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter aphrophilus, with secondary brain abscess and spontaneous rupture into the ventricles causing PV.
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spelling doaj-art-68aeca88024d4506a292f975d24f52d42025-02-03T00:59:00ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322009-01-01203e107e10910.1155/2009/971735Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature ReviewGordon W Jung0Michael D Parkins1Deirdre Church2Faculty of Medicine and Dentistry, University of Calgary, CanadaDepartment of Medicine, University of Calgary, CanadaDepartment of Medicine, University of Calgary, CanadaPyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter aphrophilus, with secondary brain abscess and spontaneous rupture into the ventricles causing PV.http://dx.doi.org/10.1155/2009/971735
spellingShingle Gordon W Jung
Michael D Parkins
Deirdre Church
Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
Canadian Journal of Infectious Diseases and Medical Microbiology
title Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
title_full Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
title_fullStr Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
title_full_unstemmed Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
title_short Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review
title_sort pyogenic ventriculitis complicating aggregatibacter aphrophilus infective endocarditis a case report and literature review
url http://dx.doi.org/10.1155/2009/971735
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AT deirdrechurch pyogenicventriculitiscomplicatingaggregatibacteraphrophilusinfectiveendocarditisacasereportandliteraturereview