Design, Synthesis, Antihyperglycemic Studies, and Docking Simulations of Benzimidazole-Thiazolidinedione Hybrids
A simple and cheap three-step procedure for the synthesis of three (5Z)-5-[3(4)-(1H-benzimidazol-2-ylmethoxy)benzylidene]-1,3-thiazolidine-2,4-diones has been described via a SN2 reaction of generally recognized as safe hydroxybenzaldehydes and 2-(chloromethyl)-1H-benzimidazole, followed by a Knoeve...
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| Main Authors: | Abraham Gutierréz-Hernández, Yelzyn Galván-Ciprés, Elix Alberto Domínguez-Mendoza, Yoshajandith Aguirre-Vidal, Samuel Estrada-Soto, Julio César Almanza-Pérez, Gabriel Navarrete-Vázquez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2019/1650145 |
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