Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species
Glycyrrhiza spp., one of the most widely used herbal medicine for centuries in the world, contain a large number of bioactive such as triterpene saponins and flavonoids which are the main constituents and show broad biological activity. The present study aimed to evaluate the phytochemical profile o...
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Ankara University
2023-01-01
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| Series: | Journal of Agricultural Sciences |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1883033 |
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| author | Fahriye Şeyma Özcan Nihat Özcan Osman Sağdıç Özlem Çetin |
| author_facet | Fahriye Şeyma Özcan Nihat Özcan Osman Sağdıç Özlem Çetin |
| author_sort | Fahriye Şeyma Özcan |
| collection | DOAJ |
| description | Glycyrrhiza spp., one of the most widely used herbal medicine for centuries in the world, contain a large number of bioactive such as triterpene saponins and flavonoids which are the main constituents and show broad biological activity. The present study aimed to evaluate the phytochemical profile of extracts from different parts (roots, stems and leaves) of all wild Glycyrrhiza spp. grown in Turkey and to reveal that other parts besides the roots are a rich source of bioactive compounds with potential use in the pharmaceutical and food industries. For this purpose, extracted bioactive compounds from different parts of five Glycyrrhiza spp. collected in different provinces of Turkey were determined and compared. The microwave-assisted extraction method, which is mentioned as a green technique and requires low solvent and extraction time, was applied. Determination of bioactives was performed using liquid chromatography- electrospray ionisation tandem mass spectrometry (LC-ESI-MS/MS). Among the collected Glycyrrhiza spp.; in leaf parts, the highest glycyrrhizin (GL) (2.05±0.07 mg g-1) and glycyrrhetinic acid (GA) (0.107±0.005 mg g-1) contents were found in Glycyrrhiza flavescens ssp. flavescens; the highest carbenoxolone (CBX) (0.133±0.006 mg g-1) and liquiritin (LQ) (1.644±0.014mg g-1) contents were in Glycyrrhiza glabra grown in Polatlı. In stem parts, the highest GL (2.735±0.04 mg g-1), CBX (0.069±0.004 mg g-1) and LQ (0.602±0.010 mg g-1) contents were determined in G. glabra plant growing in Ankara. In root parts, the highest GL (14.68±0.09 mg g-1) and LQ (9.735±0.046 mg g-1) contents were detected in G. glabra plant growing in Gaziantep while the highest GA (0.136±0.005 mg g-1) and CBX (0.188±0.067 mg g-1) contents in Glycyrrhiza flavescens ssp. antalyensis. Thus, it was determined which location in Turkey and which parts of Glycyrrhiza spp. that grow wild in Turkey can be used as a priority for the food and pharmaceutical industry with this study. |
| format | Article |
| id | doaj-art-68a498a643e64047b02fafcd957813e4 |
| institution | Kabale University |
| issn | 1300-7580 2148-9297 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Ankara University |
| record_format | Article |
| series | Journal of Agricultural Sciences |
| spelling | doaj-art-68a498a643e64047b02fafcd957813e42025-08-20T03:33:30ZengAnkara UniversityJournal of Agricultural Sciences1300-75802148-92972023-01-0129133534210.15832/ankutbd.97204845Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza SpeciesFahriye Şeyma Özcan0Nihat Özcan1Osman Sağdıç2Özlem Çetin3TUBITAK MARMARA RESEARCH CENTER FOOD INSTITUTETUBITAK MARMARA RESEARCH CENTER FOOD INSTITUTEYILDIZ TECHNICAL UNIVERSITYSELCUK UNIVERSITY, FACULTY OF SCIENCEGlycyrrhiza spp., one of the most widely used herbal medicine for centuries in the world, contain a large number of bioactive such as triterpene saponins and flavonoids which are the main constituents and show broad biological activity. The present study aimed to evaluate the phytochemical profile of extracts from different parts (roots, stems and leaves) of all wild Glycyrrhiza spp. grown in Turkey and to reveal that other parts besides the roots are a rich source of bioactive compounds with potential use in the pharmaceutical and food industries. For this purpose, extracted bioactive compounds from different parts of five Glycyrrhiza spp. collected in different provinces of Turkey were determined and compared. The microwave-assisted extraction method, which is mentioned as a green technique and requires low solvent and extraction time, was applied. Determination of bioactives was performed using liquid chromatography- electrospray ionisation tandem mass spectrometry (LC-ESI-MS/MS). Among the collected Glycyrrhiza spp.; in leaf parts, the highest glycyrrhizin (GL) (2.05±0.07 mg g-1) and glycyrrhetinic acid (GA) (0.107±0.005 mg g-1) contents were found in Glycyrrhiza flavescens ssp. flavescens; the highest carbenoxolone (CBX) (0.133±0.006 mg g-1) and liquiritin (LQ) (1.644±0.014mg g-1) contents were in Glycyrrhiza glabra grown in Polatlı. In stem parts, the highest GL (2.735±0.04 mg g-1), CBX (0.069±0.004 mg g-1) and LQ (0.602±0.010 mg g-1) contents were determined in G. glabra plant growing in Ankara. In root parts, the highest GL (14.68±0.09 mg g-1) and LQ (9.735±0.046 mg g-1) contents were detected in G. glabra plant growing in Gaziantep while the highest GA (0.136±0.005 mg g-1) and CBX (0.188±0.067 mg g-1) contents in Glycyrrhiza flavescens ssp. antalyensis. Thus, it was determined which location in Turkey and which parts of Glycyrrhiza spp. that grow wild in Turkey can be used as a priority for the food and pharmaceutical industry with this study.https://dergipark.org.tr/tr/download/article-file/1883033glycyrrhizamicrowave-assisted extractionbioactive compoundslc-esi-ms/ms |
| spellingShingle | Fahriye Şeyma Özcan Nihat Özcan Osman Sağdıç Özlem Çetin Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species Journal of Agricultural Sciences glycyrrhiza microwave-assisted extraction bioactive compounds lc-esi-ms/ms |
| title | Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species |
| title_full | Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species |
| title_fullStr | Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species |
| title_full_unstemmed | Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species |
| title_short | Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species |
| title_sort | determination and comparison of bioactive compounds in different parts of glycyrrhiza species |
| topic | glycyrrhiza microwave-assisted extraction bioactive compounds lc-esi-ms/ms |
| url | https://dergipark.org.tr/tr/download/article-file/1883033 |
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