Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India

Objectives: This cross-sectional community based study was conducted to estimate the prevalence of consumption habits for non tobacco pan masala (ASU) and the risk of developing oral precancer in North India. Methods: This study was conducted in the old town of Lucknow city in the state of Uttar Pra...

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Main Authors: Divya Mehrotra, Sumit Kumar, Shambhavi Mishra, Sandeep Kumar, Prashant Mathur, C.M. Pandey, Arvind Pandey, Kishore Chaudhry
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Oral Biology and Craniofacial Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212426816301725
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author Divya Mehrotra
Sumit Kumar
Shambhavi Mishra
Sandeep Kumar
Prashant Mathur
C.M. Pandey
Arvind Pandey
Kishore Chaudhry
author_facet Divya Mehrotra
Sumit Kumar
Shambhavi Mishra
Sandeep Kumar
Prashant Mathur
C.M. Pandey
Arvind Pandey
Kishore Chaudhry
author_sort Divya Mehrotra
collection DOAJ
description Objectives: This cross-sectional community based study was conducted to estimate the prevalence of consumption habits for non tobacco pan masala (ASU) and the risk of developing oral precancer in North India. Methods: This study was conducted in the old town of Lucknow city in the state of Uttar Pradesh in India. Subjects residing for more than 6 months and aged 15 years or above, were enrolled in the study after their informed consent. A two page survey tool was used to collect the data. A three times more matched sample of non users was randomly obtained from this data to analyze and compare the final results. Results: 0.45 million subjects were surveyed. Majority of tobacco users were in the age group of 20–35 years among males and 35–39 years among females. Consumption of non tobacco pan masala among males as well as females was most common in 15–19 years of age group. Prevalence of oral precancer (leukoplakia, submucous fibrosis, erythroplakia, lichen planus, smokers palate and verrucous hyperplasia) was 3.17% in non tobacco pan masala users and 12.22% in tobacco users. The odds of developing oral precancer in non tobacco pan masala users was 20.71 (18.79–22.82) and in tobacco users was 88.07 (84.02–92.31) at 95% confidence interval against non users of both. Conclusion: The odds of developing oral precancer even with consumption of pan masala is high, even when it is consumed without tobacco. It is hence recommended to discourage this habit.
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spelling doaj-art-689bd6c61cd54e50bd5fc3a0e963997c2025-08-20T02:50:27ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682017-01-0171131810.1016/j.jobcr.2016.12.003Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North IndiaDivya Mehrotra0Sumit Kumar1Shambhavi Mishra2Sandeep Kumar3Prashant Mathur4C.M. Pandey5Arvind Pandey6Kishore Chaudhry7Department of Oral & Maxillofacial Surgery, King George's Medical University, Lucknow, UP 226003, India; Corresponding author.Department of Oral & Maxillofacial Surgery, King George's Medical University, Lucknow, UP 226003, IndiaDepartment of Biostatistics, University of Lucknow, UP, IndiaAll India Institute of Medical Sciences (AIIMS), IndiaNational Centre for Diseases Informatics & Research (NCRP), ICMR, IndiaDepartment of Biostatistics and Health Informatics, SGPGIMS, Lucknow, IndiaNational Institute of Medical Statistics, ICMR, Ansari Nagar, New Delhi 110 029, IndiaRoseman University of Health Sciences, Henderson, NV, United StatesObjectives: This cross-sectional community based study was conducted to estimate the prevalence of consumption habits for non tobacco pan masala (ASU) and the risk of developing oral precancer in North India. Methods: This study was conducted in the old town of Lucknow city in the state of Uttar Pradesh in India. Subjects residing for more than 6 months and aged 15 years or above, were enrolled in the study after their informed consent. A two page survey tool was used to collect the data. A three times more matched sample of non users was randomly obtained from this data to analyze and compare the final results. Results: 0.45 million subjects were surveyed. Majority of tobacco users were in the age group of 20–35 years among males and 35–39 years among females. Consumption of non tobacco pan masala among males as well as females was most common in 15–19 years of age group. Prevalence of oral precancer (leukoplakia, submucous fibrosis, erythroplakia, lichen planus, smokers palate and verrucous hyperplasia) was 3.17% in non tobacco pan masala users and 12.22% in tobacco users. The odds of developing oral precancer in non tobacco pan masala users was 20.71 (18.79–22.82) and in tobacco users was 88.07 (84.02–92.31) at 95% confidence interval against non users of both. Conclusion: The odds of developing oral precancer even with consumption of pan masala is high, even when it is consumed without tobacco. It is hence recommended to discourage this habit.http://www.sciencedirect.com/science/article/pii/S2212426816301725Pan masalaOral precancerPotentially malignant disorderPrevalenceOdds ratio
spellingShingle Divya Mehrotra
Sumit Kumar
Shambhavi Mishra
Sandeep Kumar
Prashant Mathur
C.M. Pandey
Arvind Pandey
Kishore Chaudhry
Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
Journal of Oral Biology and Craniofacial Research
Pan masala
Oral precancer
Potentially malignant disorder
Prevalence
Odds ratio
title Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
title_full Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
title_fullStr Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
title_full_unstemmed Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
title_short Pan masala habits and risk of oral precancer: A cross-sectional survey in 0.45 million people of North India
title_sort pan masala habits and risk of oral precancer a cross sectional survey in 0 45 million people of north india
topic Pan masala
Oral precancer
Potentially malignant disorder
Prevalence
Odds ratio
url http://www.sciencedirect.com/science/article/pii/S2212426816301725
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