SOLUTION OF THE PROBLEM OF PSEUDOMONAS INFECTION IN CHILDREN WITH CYSTIC FIBROSIS

A difficult problem of Pseudomonas infection antibacterial treatment in patients with cystic fibrosis and its historical aspects are discussed in this article. Different medicinal forms of antibiotics are compared; the dosages for treatment in cystic fibrosis are shown. Efficacy and safety of inhala...

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Bibliographic Details
Main Authors: O. I. Simonova, Yu. V. Gorinova, A. V. Lazareva, L. K. Katosova, N. I. Burkina, V. P. Chernevich
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2014-01-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/228
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Summary:A difficult problem of Pseudomonas infection antibacterial treatment in patients with cystic fibrosis and its historical aspects are discussed in this article. Different medicinal forms of antibiotics are compared; the dosages for treatment in cystic fibrosis are shown. Efficacy and safety of inhalation form of tobramycin solution in patients with cystic fibrosis and chronic Pseudomonas infection are considered. Appropriateness of its administration in order to eradicate Pseudomonas aeruginosa as soon as it is found in the sputum, as well as in chronic persistence of this pathogen to prevent relapses of bronchopulmonary process and improvement of pulmonary function and microbiological stability is shown. The authors demonstrate their own data on usage of this drug, confirming its high tolerability and clinical effect.
ISSN:1682-5527
1682-5535