The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

Lactate, traditionally viewed as a byproduct of glycolysis, is increasingly recognized as a pivotal regulatory factor in cancer biology. This study addresses the limited understanding of lactate metabolism-related genes in head and neck squamous cell carcinoma (HNSC) by constructing a prognostic ris...

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Bibliographic Details
Main Authors: Jian Xiao, Wei Li, Guolin Tan, Ru Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
head and neck squamous cell carcinoma
lactic acid metabolism score
prognostic risk model
risk score
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1540841/full
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