Synchrotron-based X-ray 3D phase contrast imaging and analysis of transmural myocardial tissue from heart failure patients

Synchrotron-based X-ray 3D phase contrast imaging and analysis of transmural myocardial tissue from heart failure patients

Abstract Synchrotron-based X-ray phase contrast imaging (X-PCI) is a non-destructive imaging modality that can provide high resolution three-dimensional (3D) visualisation of transmural myocardial tissue, collagen matrix reconstruction, and quantification of myocyte aggregate orientation (‘myomappin...

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Bibliographic Details
Main Authors: Nikola Skreb, Filip Loncaric, Kan Yan Chloe Li, Anne Bonnin, Hector Dejea, Patricia Garcia-Canadilla, Ivana Ilic, Hrvoje Gasparovic, Davor Milicic, Bart Bijnens, Andrew C. Cook, Ivo Planinc, Maja Cikes
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Heart failure
Cardiomyopathy
Heart transplantation
Left ventricular assist device
X-ray phase contrast imaging
Histopathology
Online Access:https://doi.org/10.1038/s41598-025-04012-5
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