Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis.

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis.

<h4>Background</h4>Guidelines recommend intensive blood pressure (BP) lowering in patients at high risk. While placebo-controlled trials have demonstrated 22% reductions in coronary heart disease (CHD) and stroke associated with a 10-mmHg difference in systolic BP, it is unclear if more...

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Main Authors: Jicheng Lv, Bruce Neal, Parya Ehteshami, Toshiharu Ninomiya, Mark Woodward, Anthony Rodgers, Haiyan Wang, Stephen MacMahon, Fiona Turnbull, Graham Hillis, John Chalmers, Vlado Perkovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001293
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