Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World
Obesity hypoventilation syndrome (OHS) is a multifaceted condition characterized by significant respiratory, cardiovascular, and psychological consequences. Positive airway pressure (PAP) therapy remains the cornerstone treatment, improving respiratory function, neurocognition, and mental health dis...
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MDPI AG
2025-02-01
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| Series: | Behavioral Sciences |
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| Online Access: | https://www.mdpi.com/2076-328X/15/3/285 |
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| author | Elvia Battaglia Valentina Poletti Elena Compalati Matteo Azzollini Eleonora Volpato |
| author_facet | Elvia Battaglia Valentina Poletti Elena Compalati Matteo Azzollini Eleonora Volpato |
| author_sort | Elvia Battaglia |
| collection | DOAJ |
| description | Obesity hypoventilation syndrome (OHS) is a multifaceted condition characterized by significant respiratory, cardiovascular, and psychological consequences. Positive airway pressure (PAP) therapy remains the cornerstone treatment, improving respiratory function, neurocognition, and mental health disorders such as depression and anxiety. However, its long-term impact on quality of life, physical activity, and broader health outcomes is not fully understood. Challenges such as residual apnoea/hypopnea index, reduced physical activity, and impaired quality of life persist despite high adherence rates. Factors like hypercapnia and daytime respiratory symptoms play a pivotal role in patient outcomes, underscoring the need for strategies beyond adherence alone. This review explores the interplay between OHS, heart failure, and sleep dysfunction, advocating for personalized PAP settings, targeted management of residual respiratory events, and enhanced patient education. Digital health technologies, including remote monitoring and feedback systems, present promising tools to optimize care delivery and foster holistic management. By integrating physiological, psychological, and digital health perspectives, this narrative review aims to advance understanding and improve outcomes for patients with OHS and other complex sleep-disordered breathing conditions. |
| format | Article |
| id | doaj-art-6879902e4ac34d2186b5111fc7426cd8 |
| institution | DOAJ |
| issn | 2076-328X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Behavioral Sciences |
| spelling | doaj-art-6879902e4ac34d2186b5111fc7426cd82025-08-20T02:42:35ZengMDPI AGBehavioral Sciences2076-328X2025-02-0115328510.3390/bs15030285Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health WorldElvia Battaglia0Valentina Poletti1Elena Compalati2Matteo Azzollini3Eleonora Volpato4IRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, ItalySleep Center, Centro Diagnostico Italiano—C.D.I., 20147 Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, ItalyObesity hypoventilation syndrome (OHS) is a multifaceted condition characterized by significant respiratory, cardiovascular, and psychological consequences. Positive airway pressure (PAP) therapy remains the cornerstone treatment, improving respiratory function, neurocognition, and mental health disorders such as depression and anxiety. However, its long-term impact on quality of life, physical activity, and broader health outcomes is not fully understood. Challenges such as residual apnoea/hypopnea index, reduced physical activity, and impaired quality of life persist despite high adherence rates. Factors like hypercapnia and daytime respiratory symptoms play a pivotal role in patient outcomes, underscoring the need for strategies beyond adherence alone. This review explores the interplay between OHS, heart failure, and sleep dysfunction, advocating for personalized PAP settings, targeted management of residual respiratory events, and enhanced patient education. Digital health technologies, including remote monitoring and feedback systems, present promising tools to optimize care delivery and foster holistic management. By integrating physiological, psychological, and digital health perspectives, this narrative review aims to advance understanding and improve outcomes for patients with OHS and other complex sleep-disordered breathing conditions.https://www.mdpi.com/2076-328X/15/3/285obesity hypoventilation syndromeheart failuresleep dysfunctiondigital healthnarrative review |
| spellingShingle | Elvia Battaglia Valentina Poletti Elena Compalati Matteo Azzollini Eleonora Volpato Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World Behavioral Sciences obesity hypoventilation syndrome heart failure sleep dysfunction digital health narrative review |
| title | Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World |
| title_full | Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World |
| title_fullStr | Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World |
| title_full_unstemmed | Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World |
| title_short | Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World |
| title_sort | unmasking the complex interplay of obesity hypoventilation syndrome heart failure and sleep dysfunction a physiological and psychological perspective in a digital health world |
| topic | obesity hypoventilation syndrome heart failure sleep dysfunction digital health narrative review |
| url | https://www.mdpi.com/2076-328X/15/3/285 |
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