Anaplastic thyroid cancer: current capabilities of an oncologist

Continuous development of oncology as a science in the last decades and years led to noticeable improvement in treatment outcomes for patients with various malignant tumors. Diagnostics, surgery, radiotherapy significantly contributed to this improvement, however they cannot be compared to the progr...

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Main Authors: A. L. Pylev, D. S. Romanov, N. V. Lasunin, D. A. Balaeva, M. P. Kazakov
Format: Article
Language:Russian
Published: ABV-press 2023-06-01
Series:Опухоли головы и шеи
Subjects:
Online Access:https://ogsh.abvpress.ru/jour/article/view/874
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author A. L. Pylev
D. S. Romanov
N. V. Lasunin
D. A. Balaeva
M. P. Kazakov
author_facet A. L. Pylev
D. S. Romanov
N. V. Lasunin
D. A. Balaeva
M. P. Kazakov
author_sort A. L. Pylev
collection DOAJ
description Continuous development of oncology as a science in the last decades and years led to noticeable improvement in treatment outcomes for patients with various malignant tumors. Diagnostics, surgery, radiotherapy significantly contributed to this improvement, however they cannot be compared to the progress achieved through advancements in our knowledge of genetic structure of tumors and subsequent advancements in pharmacology which allowed to achieve qualitatively better survival in oncological patients. These advancements did not leave out such a serious and highly lethal, though fortunately rare, disease as anaplastic thyroid cancer. This article is dedicated to the possibilities of using checkpoint inhibitors in treatment of this pathology to increase expected life span of the patients.
format Article
id doaj-art-687531793fc647c39c141d1d268bfa89
institution DOAJ
issn 2222-1468
2411-4634
language Russian
publishDate 2023-06-01
publisher ABV-press
record_format Article
series Опухоли головы и шеи
spelling doaj-art-687531793fc647c39c141d1d268bfa892025-08-20T03:01:13ZrusABV-pressОпухоли головы и шеи2222-14682411-46342023-06-0113111612510.17650/2222-1468-2023-13-1-116-125544Anaplastic thyroid cancer: current capabilities of an oncologistA. L. Pylev0D. S. Romanov1N. V. Lasunin2D. A. Balaeva3M. P. Kazakov4Center for Innovative Medical TechnologiesCenter for Innovative Medical Technologies; Central Clinical Hospital of Russian Railways-Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaN.N. Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of RussiaCentral Clinical Hospital of Russian Railways-Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaCenter for Innovative Medical TechnologiesContinuous development of oncology as a science in the last decades and years led to noticeable improvement in treatment outcomes for patients with various malignant tumors. Diagnostics, surgery, radiotherapy significantly contributed to this improvement, however they cannot be compared to the progress achieved through advancements in our knowledge of genetic structure of tumors and subsequent advancements in pharmacology which allowed to achieve qualitatively better survival in oncological patients. These advancements did not leave out such a serious and highly lethal, though fortunately rare, disease as anaplastic thyroid cancer. This article is dedicated to the possibilities of using checkpoint inhibitors in treatment of this pathology to increase expected life span of the patients.https://ogsh.abvpress.ru/jour/article/view/874anaplastic thyroid cancercheckpoint inhibitorspembrolizumabmetastatic brain damage
spellingShingle A. L. Pylev
D. S. Romanov
N. V. Lasunin
D. A. Balaeva
M. P. Kazakov
Anaplastic thyroid cancer: current capabilities of an oncologist
Опухоли головы и шеи
anaplastic thyroid cancer
checkpoint inhibitors
pembrolizumab
metastatic brain damage
title Anaplastic thyroid cancer: current capabilities of an oncologist
title_full Anaplastic thyroid cancer: current capabilities of an oncologist
title_fullStr Anaplastic thyroid cancer: current capabilities of an oncologist
title_full_unstemmed Anaplastic thyroid cancer: current capabilities of an oncologist
title_short Anaplastic thyroid cancer: current capabilities of an oncologist
title_sort anaplastic thyroid cancer current capabilities of an oncologist
topic anaplastic thyroid cancer
checkpoint inhibitors
pembrolizumab
metastatic brain damage
url https://ogsh.abvpress.ru/jour/article/view/874
work_keys_str_mv AT alpylev anaplasticthyroidcancercurrentcapabilitiesofanoncologist
AT dsromanov anaplasticthyroidcancercurrentcapabilitiesofanoncologist
AT nvlasunin anaplasticthyroidcancercurrentcapabilitiesofanoncologist
AT dabalaeva anaplasticthyroidcancercurrentcapabilitiesofanoncologist
AT mpkazakov anaplasticthyroidcancercurrentcapabilitiesofanoncologist