Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
In many cell types, several cellular processes, such as differentiation of stem/precursor cells, maintenance of differentiated phenotype, motility, adhesion, growth, and survival, strictly depend on the stiffness of extracellular matrix that, in vivo, characterizes their correspondent organ and tiss...
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| Main Authors: | Angela Maria Cozzolino, Valeria Noce, Cecilia Battistelli, Alessandra Marchetti, Germana Grassi, Carla Cicchini, Marco Tripodi, Laura Amicone |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2016/5481493 |
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