A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021
BackgroundPelvic organ prolapse (POP) is a prevalent condition affecting millions of women globally. Understanding its temporal trends and regional disparities is essential for effective public health interventions.MethodsA cross-sectional analysis was conducted using data from the Global Burden of...
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Frontiers Media S.A.
2025-05-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1555946/full |
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| author | Rui Wang Wangshu Li Jinliang Yang Aziz ur Rehman Aziz Chunfang Ha |
| author_facet | Rui Wang Wangshu Li Jinliang Yang Aziz ur Rehman Aziz Chunfang Ha |
| author_sort | Rui Wang |
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| description | BackgroundPelvic organ prolapse (POP) is a prevalent condition affecting millions of women globally. Understanding its temporal trends and regional disparities is essential for effective public health interventions.MethodsA cross-sectional analysis was conducted using data from the Global Burden of Disease (GBD) study, examining trends in POP incidence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021. We analyzed the estimated annual percentage change (EAPC) and explored the association with the socio-demographic index (SDI).ResultsFrom 1990 to 2021, global POP cases increased from approximately 8.4 million to 14.0 million, while the age-standardized incidence rate (ASIR) declined from 374.84 to 317.51 per 100,000 population (EAPC = −0.46). Deaths rose from 281 to 486, but the age-standardized death rate (ASDR) remained stable. DALYs increased from 232,432 to 389,358, with a decrease in age-standardized DALY rate (EAPC = −0.59). Low-SDI regions exhibited the highest ASIR, ASDR, and DALYs in 2021.ConclusionThe global burden of pelvic organ prolapse has increased in absolute numbers, although age-standardized rates have declined. Low-SDI regions continue to face the highest burden, highlighting the need for targeted healthcare interventions. |
| format | Article |
| id | doaj-art-686167f0404346f7b028bbc2c034d09f |
| institution | DOAJ |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
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| spelling | doaj-art-686167f0404346f7b028bbc2c034d09f2025-08-20T02:56:07ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-05-011310.3389/fpubh.2025.15559461555946A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021Rui Wang0Wangshu Li1Jinliang Yang2Aziz ur Rehman Aziz3Chunfang Ha4General Hospital of Ningxia Medical University, Yinchuan, ChinaKey Laboratory for Early Diagnosis and Biotherapy of Malignant Tumors in Children and Women, Dalian Women and Children’s Medical Group, Dalian, Liaoning, ChinaGeneral Hospital of Ningxia Medical University, Yinchuan, ChinaKey Laboratory for Early Diagnosis and Biotherapy of Malignant Tumors in Children and Women, Dalian Women and Children’s Medical Group, Dalian, Liaoning, ChinaGeneral Hospital of Ningxia Medical University, Yinchuan, ChinaBackgroundPelvic organ prolapse (POP) is a prevalent condition affecting millions of women globally. Understanding its temporal trends and regional disparities is essential for effective public health interventions.MethodsA cross-sectional analysis was conducted using data from the Global Burden of Disease (GBD) study, examining trends in POP incidence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021. We analyzed the estimated annual percentage change (EAPC) and explored the association with the socio-demographic index (SDI).ResultsFrom 1990 to 2021, global POP cases increased from approximately 8.4 million to 14.0 million, while the age-standardized incidence rate (ASIR) declined from 374.84 to 317.51 per 100,000 population (EAPC = −0.46). Deaths rose from 281 to 486, but the age-standardized death rate (ASDR) remained stable. DALYs increased from 232,432 to 389,358, with a decrease in age-standardized DALY rate (EAPC = −0.59). Low-SDI regions exhibited the highest ASIR, ASDR, and DALYs in 2021.ConclusionThe global burden of pelvic organ prolapse has increased in absolute numbers, although age-standardized rates have declined. Low-SDI regions continue to face the highest burden, highlighting the need for targeted healthcare interventions.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1555946/fullpelvic organ prolapseglobal burdenincidencemortalitydisability adjusted life yearssocio-demographic index |
| spellingShingle | Rui Wang Wangshu Li Jinliang Yang Aziz ur Rehman Aziz Chunfang Ha A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 Frontiers in Public Health pelvic organ prolapse global burden incidence mortality disability adjusted life years socio-demographic index |
| title | A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 |
| title_full | A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 |
| title_fullStr | A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 |
| title_full_unstemmed | A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 |
| title_short | A cross-sectional analysis based on GBD data: trends in the global, regional, and national burden of pelvic organ prolapse from 1990 to 2021 |
| title_sort | cross sectional analysis based on gbd data trends in the global regional and national burden of pelvic organ prolapse from 1990 to 2021 |
| topic | pelvic organ prolapse global burden incidence mortality disability adjusted life years socio-demographic index |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1555946/full |
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