A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer
Purpose: To investigate the effects of compression therapy combined with exercise for cancer patients (EXCAP) in patients with peripheral neuropathy caused by breast cancer chemotherapy. Methods: Overall, 108 patients with peripheral neuropathy after chemotherapy for breast cancer were randomly divi...
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Elsevier
2024-01-01
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| Series: | Cancer Treatment and Research Communications |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468294225000097 |
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| author | Yu Xiaoqian Hu Jiwei Zhou Lizhi Guo Baojia Guo Luyan Xu Huiqian Li Hong Fan Yijing |
| author_facet | Yu Xiaoqian Hu Jiwei Zhou Lizhi Guo Baojia Guo Luyan Xu Huiqian Li Hong Fan Yijing |
| author_sort | Yu Xiaoqian |
| collection | DOAJ |
| description | Purpose: To investigate the effects of compression therapy combined with exercise for cancer patients (EXCAP) in patients with peripheral neuropathy caused by breast cancer chemotherapy. Methods: Overall, 108 patients with peripheral neuropathy after chemotherapy for breast cancer were randomly divided into the control group (routine nursing), experimental group 1 (compression therapy), and experimental group 2 (compression therapy and EXCAP). The National Institute of Cancer Drug Toxicity Rating Scale and the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool were assessed and compared between groups. Results: The incidence of grade 0 peripheral neuropathy in both experimental groups was higher than that in controls (P < 0.001), and the incidence in group 2 was higher than that in group 1 (P < 0.001). The incidence of grade 2 disease in both experimental groups was lower than that in controls (P < 0.001). The rate of symptoms in both experimental groups after the intervention were lower than that in the control group (P < 0.001), and those in experimental group 2 were lower than those in experimental group 1 (P < 0.001). Scores regarding activities of daily living in the experimental groups were lower than those of the control group (P < 0.001), and lower in group 2 than in group 1 (P < 0.001). Conclusion: Compression therapy and EXCAP can effectively reduce the incidence of chemotherapy-induced peripheral neuropathy in patients undergoing breast cancer chemotherapy. They can both positively impact patients' daily lives and symptom experiences; however, they are more effective when combined. |
| format | Article |
| id | doaj-art-685b4eca99d3463baf8974321718b910 |
| institution | Kabale University |
| issn | 2468-2942 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cancer Treatment and Research Communications |
| spelling | doaj-art-685b4eca99d3463baf8974321718b9102025-02-09T05:00:48ZengElsevierCancer Treatment and Research Communications2468-29422024-01-0142100871A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancerYu Xiaoqian0Hu Jiwei1Zhou Lizhi2Guo Baojia3Guo Luyan4Xu Huiqian5Li Hong6Fan Yijing7North China University of Science and Technology, Tangshan 063210, ChinaTangshan People's Hospital, Tangshan 063000, ChinaTangshan People's Hospital, Tangshan 063000, China; Corresponding author at: Tangshan People's Hospital, Tangshan 063000, China.Tangshan People's Hospital, Tangshan 063000, ChinaNorth China University of Science and Technology, Tangshan 063210, ChinaNorth China University of Science and Technology, Tangshan 063210, ChinaNorth China University of Science and Technology, Tangshan 063210, ChinaNorth China University of Science and Technology, Tangshan 063210, ChinaPurpose: To investigate the effects of compression therapy combined with exercise for cancer patients (EXCAP) in patients with peripheral neuropathy caused by breast cancer chemotherapy. Methods: Overall, 108 patients with peripheral neuropathy after chemotherapy for breast cancer were randomly divided into the control group (routine nursing), experimental group 1 (compression therapy), and experimental group 2 (compression therapy and EXCAP). The National Institute of Cancer Drug Toxicity Rating Scale and the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool were assessed and compared between groups. Results: The incidence of grade 0 peripheral neuropathy in both experimental groups was higher than that in controls (P < 0.001), and the incidence in group 2 was higher than that in group 1 (P < 0.001). The incidence of grade 2 disease in both experimental groups was lower than that in controls (P < 0.001). The rate of symptoms in both experimental groups after the intervention were lower than that in the control group (P < 0.001), and those in experimental group 2 were lower than those in experimental group 1 (P < 0.001). Scores regarding activities of daily living in the experimental groups were lower than those of the control group (P < 0.001), and lower in group 2 than in group 1 (P < 0.001). Conclusion: Compression therapy and EXCAP can effectively reduce the incidence of chemotherapy-induced peripheral neuropathy in patients undergoing breast cancer chemotherapy. They can both positively impact patients' daily lives and symptom experiences; however, they are more effective when combined.http://www.sciencedirect.com/science/article/pii/S2468294225000097Breast cancerChemotherapyPeripheral neuropathyCompression therapyEXCAP |
| spellingShingle | Yu Xiaoqian Hu Jiwei Zhou Lizhi Guo Baojia Guo Luyan Xu Huiqian Li Hong Fan Yijing A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer Cancer Treatment and Research Communications Breast cancer Chemotherapy Peripheral neuropathy Compression therapy EXCAP |
| title | A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer |
| title_full | A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer |
| title_fullStr | A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer |
| title_full_unstemmed | A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer |
| title_short | A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer |
| title_sort | randomized controlled trial effects of compression therapy combined with exercise on chemotherapy induced peripheral neuropathy in patients with breast cancer |
| topic | Breast cancer Chemotherapy Peripheral neuropathy Compression therapy EXCAP |
| url | http://www.sciencedirect.com/science/article/pii/S2468294225000097 |
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