Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation

The comparative analysis of two methods of exposure of sensitization of recipients to HLA is conducted - traditional serum method, based on a limphocytotoxicity test, and the method of multiplexed analysis with the detection of results using the Luminex platform. A high sensitiveness and informing o...

Full description

Saved in:
Bibliographic Details
Main Authors: N. V. Borovkova, N. V. Doronina, N. A. Mush
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2018-08-01
Series:Трансплантология (Москва)
Subjects:
Online Access:https://www.jtransplantologiya.ru/jour/article/view/322
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849252551301529600
author N. V. Borovkova
N. V. Doronina
N. A. Mush
author_facet N. V. Borovkova
N. V. Doronina
N. A. Mush
author_sort N. V. Borovkova
collection DOAJ
description The comparative analysis of two methods of exposure of sensitization of recipients to HLA is conducted - traditional serum method, based on a limphocytotoxicity test, and the method of multiplexed analysis with the detection of results using the Luminex platform. A high sensitiveness and informing of method of antibodies determination to HLA using the Luminex platform is demonstrated.
format Article
id doaj-art-685968fbf00e41a88dd56237c61a321c
institution Kabale University
issn 2074-0506
2542-0909
language English
publishDate 2018-08-01
publisher N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
record_format Article
series Трансплантология (Москва)
spelling doaj-art-685968fbf00e41a88dd56237c61a321c2025-08-20T03:56:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0104374010.23873/2074-0506-2011-0-4-37-40309Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantationN. V. Borovkova0N. V. Doronina1N. A. Mush2Sklifosovsky Research Institute for Emergency MedicineSklifosovsky Research Institute for Emergency MedicineSklifosovsky Research Institute for Emergency MedicineThe comparative analysis of two methods of exposure of sensitization of recipients to HLA is conducted - traditional serum method, based on a limphocytotoxicity test, and the method of multiplexed analysis with the detection of results using the Luminex platform. A high sensitiveness and informing of method of antibodies determination to HLA using the Luminex platform is demonstrated.https://www.jtransplantologiya.ru/jour/article/view/322antibodies to hlalimphocytotoxicity testmultiplexed analysisthe luminex platform
spellingShingle N. V. Borovkova
N. V. Doronina
N. A. Mush
Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
Трансплантология (Москва)
antibodies to hla
limphocytotoxicity test
multiplexed analysis
the luminex platform
title Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
title_full Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
title_fullStr Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
title_full_unstemmed Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
title_short Methods to determine the sensitization to HLA in the recipients on the waiting list for organ transplantation
title_sort methods to determine the sensitization to hla in the recipients on the waiting list for organ transplantation
topic antibodies to hla
limphocytotoxicity test
multiplexed analysis
the luminex platform
url https://www.jtransplantologiya.ru/jour/article/view/322
work_keys_str_mv AT nvborovkova methodstodeterminethesensitizationtohlaintherecipientsonthewaitinglistfororgantransplantation
AT nvdoronina methodstodeterminethesensitizationtohlaintherecipientsonthewaitinglistfororgantransplantation
AT namush methodstodeterminethesensitizationtohlaintherecipientsonthewaitinglistfororgantransplantation