Targeting Ischemia-reperfusion injury in liver transplant rejuvenation

Targeting Ischemia-reperfusion injury in liver transplant rejuvenation

Background: Hepatic ischemia-reperfusion injury (HIRI) is a multifaceted pathophysiological process involving a cascade of interconnected cellular events. The initial ischemic stress, followed by the reestablishment of blood circulation to the liver, triggers a feed-forward innate immune-driven resp...

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Bibliographic Details
Main Authors: Kenneth J. Dery, Fady Kaldas, Jerzy W. Kupiec-Weglinski
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Transplantation Reports
Subjects:
CEACAM1
Ferroptosis
Ischemia-Reperfusion Injury
Liver
NLRP3
Normothermic machine perfusion
Online Access:http://www.sciencedirect.com/science/article/pii/S245195962500006X
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