Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study
Abstract This study aimed to examine trends in the ages of menarche and menopause, and related factors, among women in the Fasa Cohort Study. We analyzed cross-sectional data from the Fasa cohort, part of the Persian cohort study, which included 11,000 Iranian adults aged 35 to 75, with 5311 being w...
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Nature Portfolio
2025-05-01
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| Online Access: | https://doi.org/10.1038/s41598-025-03435-4 |
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| author | Neda Bazyar Zahra Moradi Ali Khani Jeihooni Azizallah Dehghan |
| author_facet | Neda Bazyar Zahra Moradi Ali Khani Jeihooni Azizallah Dehghan |
| author_sort | Neda Bazyar |
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| description | Abstract This study aimed to examine trends in the ages of menarche and menopause, and related factors, among women in the Fasa Cohort Study. We analyzed cross-sectional data from the Fasa cohort, part of the Persian cohort study, which included 11,000 Iranian adults aged 35 to 75, with 5311 being women. These women were categorized into four age groups: 35–44, 45–54, 55–64, and 65–75 years. We explored changes in mean ages at menarche and menopause, along with associated factors, using SPSS 22 software and applying descriptive statistics, chi-square tests, t-tests, ANOVA, and multivariable linear regression. Results indicated a reduction in mean age at menarche from 14.16 to 13.40 years and a decline in mean age at menopause from 52.27 to 40.25 years across the same age groups, both statistically significant (p < 0.001). A significant relationship was found between age at menopause and factors such as education level, marital status, hypertension, and thyroid disease (p < 0.001). Women without a history of hypertension experienced menopause 0.84 years later than those with the condition, and those without thyroid disease had a delay of 0.75 years. Additionally, each year a woman delays having her first child corresponds to a 0.11-year increase in her age at menopause. |
| format | Article |
| id | doaj-art-684a7fbbff4b44fc994ab8d6614a03b4 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-684a7fbbff4b44fc994ab8d6614a03b42025-08-20T03:16:52ZengNature PortfolioScientific Reports2045-23222025-05-0115111010.1038/s41598-025-03435-4Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based studyNeda Bazyar0Zahra Moradi1Ali Khani Jeihooni2Azizallah Dehghan3Student Research Committee, Fasa University of Medical SciencesDepartment of Midwifery, School of Nursing, Fasa University of Medical SciencesDepartment of Public Health, School of Health, Shiraz University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesAbstract This study aimed to examine trends in the ages of menarche and menopause, and related factors, among women in the Fasa Cohort Study. We analyzed cross-sectional data from the Fasa cohort, part of the Persian cohort study, which included 11,000 Iranian adults aged 35 to 75, with 5311 being women. These women were categorized into four age groups: 35–44, 45–54, 55–64, and 65–75 years. We explored changes in mean ages at menarche and menopause, along with associated factors, using SPSS 22 software and applying descriptive statistics, chi-square tests, t-tests, ANOVA, and multivariable linear regression. Results indicated a reduction in mean age at menarche from 14.16 to 13.40 years and a decline in mean age at menopause from 52.27 to 40.25 years across the same age groups, both statistically significant (p < 0.001). A significant relationship was found between age at menopause and factors such as education level, marital status, hypertension, and thyroid disease (p < 0.001). Women without a history of hypertension experienced menopause 0.84 years later than those with the condition, and those without thyroid disease had a delay of 0.75 years. Additionally, each year a woman delays having her first child corresponds to a 0.11-year increase in her age at menopause.https://doi.org/10.1038/s41598-025-03435-4Menarche age changesMenopause age changesPopulation-based study |
| spellingShingle | Neda Bazyar Zahra Moradi Ali Khani Jeihooni Azizallah Dehghan Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study Scientific Reports Menarche age changes Menopause age changes Population-based study |
| title | Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study |
| title_full | Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study |
| title_fullStr | Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study |
| title_full_unstemmed | Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study |
| title_short | Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study |
| title_sort | trends in age at natural menopause and menarche and related factors in iran results from a population based study |
| topic | Menarche age changes Menopause age changes Population-based study |
| url | https://doi.org/10.1038/s41598-025-03435-4 |
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