Histopathology of Placentae in Pre-Eclampsia: A Review

Preeclampsia (PE) is a pregnancy related complex multisystemic disorder with a triad of symptoms including increased blood pressure, oedema, and proteinuria phenotypically observed after 20 weeks of gestation. The disorder worsens amongst the early onset patients PE (< 34 weeks). The pla...

Full description

Saved in:
Bibliographic Details
Main Author: C Krishnaveni
Format: Article
Language:English
Published: Sri Devaraj Urs Academy of Higher Education and Research 2022-03-01
Series:Journal of Clinical and Biomedical Sciences
Online Access:https://jcbsonline.ac.in/articles/histopathology-of-placentae-in-pre-eclampsia-a-review
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849393875228033024
author C Krishnaveni
author_facet C Krishnaveni
author_sort C Krishnaveni
collection DOAJ
description Preeclampsia (PE) is a pregnancy related complex multisystemic disorder with a triad of symptoms including increased blood pressure, oedema, and proteinuria phenotypically observed after 20 weeks of gestation. The disorder worsens amongst the early onset patients PE (< 34 weeks). The placenta shares more responsibility for the cause of PE. The placenta is an essential organ for pregnancy and assists in the development of the fetus. It shares the same stress and strain to which the fetus is exposed. Any disease which affects the mother has a great impact on the placenta and also placenta acts as a future evidence of mother and fetus health. Therefore careful observation of histopathological changes can provide clinically useful information to pave the way for pathophysiology of PE. So the histopathological parameters like distal villous hypoplasia, accelerated villous maturity, increase in syncytial knots, immature villi, chorangiosis, fibrin deposition, infarction, and calcification are evident in histopathological observations of PE placentae. Keywords: Histopathology of placenta, Pre-eclampsia, Distal Villous Hypoplasia, Chorionic Villi, Villous maturity.
format Article
id doaj-art-684827735a654df99cee7f58e45f65a2
institution Kabale University
issn 2231-4180
2319-2453
language English
publishDate 2022-03-01
publisher Sri Devaraj Urs Academy of Higher Education and Research
record_format Article
series Journal of Clinical and Biomedical Sciences
spelling doaj-art-684827735a654df99cee7f58e45f65a22025-08-20T03:40:15ZengSri Devaraj Urs Academy of Higher Education and ResearchJournal of Clinical and Biomedical Sciences2231-41802319-24532022-03-0112141010.58739/jcbs/v12i1.8Histopathology of Placentae in Pre-Eclampsia: A ReviewC Krishnaveni Preeclampsia (PE) is a pregnancy related complex multisystemic disorder with a triad of symptoms including increased blood pressure, oedema, and proteinuria phenotypically observed after 20 weeks of gestation. The disorder worsens amongst the early onset patients PE (< 34 weeks). The placenta shares more responsibility for the cause of PE. The placenta is an essential organ for pregnancy and assists in the development of the fetus. It shares the same stress and strain to which the fetus is exposed. Any disease which affects the mother has a great impact on the placenta and also placenta acts as a future evidence of mother and fetus health. Therefore careful observation of histopathological changes can provide clinically useful information to pave the way for pathophysiology of PE. So the histopathological parameters like distal villous hypoplasia, accelerated villous maturity, increase in syncytial knots, immature villi, chorangiosis, fibrin deposition, infarction, and calcification are evident in histopathological observations of PE placentae. Keywords: Histopathology of placenta, Pre-eclampsia, Distal Villous Hypoplasia, Chorionic Villi, Villous maturity.https://jcbsonline.ac.in/articles/histopathology-of-placentae-in-pre-eclampsia-a-review
spellingShingle C Krishnaveni
Histopathology of Placentae in Pre-Eclampsia: A Review
Journal of Clinical and Biomedical Sciences
title Histopathology of Placentae in Pre-Eclampsia: A Review
title_full Histopathology of Placentae in Pre-Eclampsia: A Review
title_fullStr Histopathology of Placentae in Pre-Eclampsia: A Review
title_full_unstemmed Histopathology of Placentae in Pre-Eclampsia: A Review
title_short Histopathology of Placentae in Pre-Eclampsia: A Review
title_sort histopathology of placentae in pre eclampsia a review
url https://jcbsonline.ac.in/articles/histopathology-of-placentae-in-pre-eclampsia-a-review
work_keys_str_mv AT ckrishnaveni histopathologyofplacentaeinpreeclampsiaareview