Reconstitution of Methionine Cycle With ATP Regeneration for Whole‐Cell Catalysis of Creatine Production in Engineered Escherichia coli

Reconstitution of Methionine Cycle With ATP Regeneration for Whole‐Cell Catalysis of Creatine Production in Engineered Escherichia coli

ABSTRACT Creatine (CR) is a naturally occurring amino acid derivative that plays a key role in cellular energy homeostasis, which has wide‐ranging applications in food and medicine. Currently, the lack of green and sustainable CR biomanufacturing methods has led to reliance on chemical methods for i...

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Bibliographic Details
Main Authors: Yuhua Sheng, Yaokang Wu, Linpei Zhang, Xueqin Lv, Jianghua Li, Long Liu, Guocheng Du, Jian Chen, Yanfeng Liu
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Microbial Biotechnology
Subjects:
ATP regeneration
creatine bioproduction
methionine cycle
whole‐cell biocatalysis
Online Access:https://doi.org/10.1111/1751-7915.70145
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