Ventilator-Associated Pneumonia in Children
Objective: to elucidate a role of the most significant risk factors in the development of outcomes of ventilator-associated pneumonia (VAP). Subjects and materials. In 1997—2006, the intensive care units of Novokuznetsk observed 77 children with VAP (a study group) and 30 patients without VANP who w...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-06-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1028 |
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| author | O. I. Andriyanova I. G. Khamin Yu. A. Churlyaev F. K. Manerov |
| author_facet | O. I. Andriyanova I. G. Khamin Yu. A. Churlyaev F. K. Manerov |
| author_sort | O. I. Andriyanova |
| collection | DOAJ |
| description | Objective: to elucidate a role of the most significant risk factors in the development of outcomes of ventilator-associated pneumonia (VAP). Subjects and materials. In 1997—2006, the intensive care units of Novokuznetsk observed 77 children with VAP (a study group) and 30 patients without VANP who were on artificial ventilation (AV) for more than 2 days (a control group). In the group of VAP, there was a preponderance of babies of the first year of life (p=0.0097), children with the baseline pathology (p=0.0145), severe underlying diseases, multiply organ dysfunction (p=0.0388) who were long on AV. Sputum gram-negative microorganisms were shown to be isolated statistically significantly more frequently (p=0.0005). Conclusion. Antibacterial therapy should be started with a combination of reserve antibiotics by the de-escalation scheme. In children with VAP, the predictors of poor prognosis are a bilateral process; the preservation of fever in the patients on adequate antibacterial therapy and/or the preservation of the microorganism; a low (<300) oxygenation index; no positive X-ray changes. In VAP, attributive mortality was 10.4%. Key words: children, ventilator-associated pneumonia, risk factors, gram-negative microorganisms, oxygenation index, mortality. |
| format | Article |
| id | doaj-art-6820bd36d6524fb69e7c75b79e5da534 |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2007-06-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-6820bd36d6524fb69e7c75b79e5da5342025-08-20T03:18:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-06-013310.15360/1813-9779-2007-3-851028Ventilator-Associated Pneumonia in ChildrenO. I. AndriyanovaI. G. KhaminYu. A. ChurlyaevF. K. ManerovObjective: to elucidate a role of the most significant risk factors in the development of outcomes of ventilator-associated pneumonia (VAP). Subjects and materials. In 1997—2006, the intensive care units of Novokuznetsk observed 77 children with VAP (a study group) and 30 patients without VANP who were on artificial ventilation (AV) for more than 2 days (a control group). In the group of VAP, there was a preponderance of babies of the first year of life (p=0.0097), children with the baseline pathology (p=0.0145), severe underlying diseases, multiply organ dysfunction (p=0.0388) who were long on AV. Sputum gram-negative microorganisms were shown to be isolated statistically significantly more frequently (p=0.0005). Conclusion. Antibacterial therapy should be started with a combination of reserve antibiotics by the de-escalation scheme. In children with VAP, the predictors of poor prognosis are a bilateral process; the preservation of fever in the patients on adequate antibacterial therapy and/or the preservation of the microorganism; a low (<300) oxygenation index; no positive X-ray changes. In VAP, attributive mortality was 10.4%. Key words: children, ventilator-associated pneumonia, risk factors, gram-negative microorganisms, oxygenation index, mortality.https://www.reanimatology.com/rmt/article/view/1028 |
| spellingShingle | O. I. Andriyanova I. G. Khamin Yu. A. Churlyaev F. K. Manerov Ventilator-Associated Pneumonia in Children Общая реаниматология |
| title | Ventilator-Associated Pneumonia in Children |
| title_full | Ventilator-Associated Pneumonia in Children |
| title_fullStr | Ventilator-Associated Pneumonia in Children |
| title_full_unstemmed | Ventilator-Associated Pneumonia in Children |
| title_short | Ventilator-Associated Pneumonia in Children |
| title_sort | ventilator associated pneumonia in children |
| url | https://www.reanimatology.com/rmt/article/view/1028 |
| work_keys_str_mv | AT oiandriyanova ventilatorassociatedpneumoniainchildren AT igkhamin ventilatorassociatedpneumoniainchildren AT yuachurlyaev ventilatorassociatedpneumoniainchildren AT fkmanerov ventilatorassociatedpneumoniainchildren |