The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study

Background/Objectives: Emergence delirium (ED) is one of the most frequent postoperative complications in pediatric patients after general anesthesia. In adults, a deeper intraoperative level of anesthesia has been reported as an independent predictor of postoperative delirium. However, the effect o...

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Main Authors: Yea-Ji Lee, Jung-Won Hwang, Sang-Hwan Do, Hyo-Seok Na
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/1/63
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author Yea-Ji Lee
Jung-Won Hwang
Sang-Hwan Do
Hyo-Seok Na
author_facet Yea-Ji Lee
Jung-Won Hwang
Sang-Hwan Do
Hyo-Seok Na
author_sort Yea-Ji Lee
collection DOAJ
description Background/Objectives: Emergence delirium (ED) is one of the most frequent postoperative complications in pediatric patients after general anesthesia. In adults, a deeper intraoperative level of anesthesia has been reported as an independent predictor of postoperative delirium. However, the effect of anesthetic depth on ED has rarely been demonstrated in the pediatric population. We evaluated whether the depth of general anesthesia could affect the occurrence of emergence delirium (ED). Methods: Patients aged 3–5 years, scheduled for strabismus surgery were enrolled in this prospective observational study. Intraoperative bispectral index (BIS) was monitored, and the pediatric anesthesia emergence delirium (PAED) scale was evaluated. When the PAED scale was 10 or more, it was designated as an ED case. Results: According to the intraoperative mean BIS range, enrolled patients were divided into two groups: the low BIS (BIS < 40; <i>n</i> = 28) and the normal BIS (BIS 40–60; <i>n</i> = 34) group. The incidence of ED was comparable between the two groups (67.6% vs. 67.9%, odds ratio = 0.99, 95% CI = 0.34–2.89, <i>p</i> = 0.986). Conclusions: The intraoperative anesthetic depth did not seem to affect the occurrence of ED in pediatric patients undergoing strabismus surgery under general anesthesia. Future studies with a larger sample size are necessary for more authentic results.
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spelling doaj-art-6813153c63b94fefbb37ab464e16bb542025-01-24T13:23:53ZengMDPI AGBiomedicines2227-90592024-12-011316310.3390/biomedicines13010063The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational StudyYea-Ji Lee0Jung-Won Hwang1Sang-Hwan Do2Hyo-Seok Na3Department of Anesthesiology and Pain Medicine, Konkuk University Medical Centre, Seoul 05030, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of KoreaBackground/Objectives: Emergence delirium (ED) is one of the most frequent postoperative complications in pediatric patients after general anesthesia. In adults, a deeper intraoperative level of anesthesia has been reported as an independent predictor of postoperative delirium. However, the effect of anesthetic depth on ED has rarely been demonstrated in the pediatric population. We evaluated whether the depth of general anesthesia could affect the occurrence of emergence delirium (ED). Methods: Patients aged 3–5 years, scheduled for strabismus surgery were enrolled in this prospective observational study. Intraoperative bispectral index (BIS) was monitored, and the pediatric anesthesia emergence delirium (PAED) scale was evaluated. When the PAED scale was 10 or more, it was designated as an ED case. Results: According to the intraoperative mean BIS range, enrolled patients were divided into two groups: the low BIS (BIS < 40; <i>n</i> = 28) and the normal BIS (BIS 40–60; <i>n</i> = 34) group. The incidence of ED was comparable between the two groups (67.6% vs. 67.9%, odds ratio = 0.99, 95% CI = 0.34–2.89, <i>p</i> = 0.986). Conclusions: The intraoperative anesthetic depth did not seem to affect the occurrence of ED in pediatric patients undergoing strabismus surgery under general anesthesia. Future studies with a larger sample size are necessary for more authentic results.https://www.mdpi.com/2227-9059/13/1/63anesthesiageneralbispectral indexchildemergence deliriumsurgical procedure
spellingShingle Yea-Ji Lee
Jung-Won Hwang
Sang-Hwan Do
Hyo-Seok Na
The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
Biomedicines
anesthesia
general
bispectral index
child
emergence delirium
surgical procedure
title The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
title_full The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
title_fullStr The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
title_full_unstemmed The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
title_short The Effect of Anesthetic Depth on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Prospective Observational Study
title_sort effect of anesthetic depth on the occurrence of emergence delirium in children undergoing strabismus surgery a prospective observational study
topic anesthesia
general
bispectral index
child
emergence delirium
surgical procedure
url https://www.mdpi.com/2227-9059/13/1/63
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