Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis
Background/Aim. Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue), balneotherapy is drawing increased attention worldwide. Being part of cl...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500095G.pdf |
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| author | Golušin Zoran Jovanović Marina Magda Nataša Stojanović Slobodan Matić Milan Petrović Aleksandra |
| author_facet | Golušin Zoran Jovanović Marina Magda Nataša Stojanović Slobodan Matić Milan Petrović Aleksandra |
| author_sort | Golušin Zoran |
| collection | DOAJ |
| description | Background/Aim. Treatment of psoriasis is very complex and there are no still
universal, nor unique treatment modalities. Apart from conventional
treatment, which includes topical calcipotriol (vitamin D3 analogue),
balneotherapy is drawing increased attention worldwide. Being part of
climatotherapy, balneotherapy is defined as the use of natural environmental
factors in the treatment of health conditions, whereas in the treatment of
psoriasis it means the use of mineral baths and peloids. The aim of this
study was to examine the therapeutic efficacy of mineral waters and peloids
of the Rusanda Spa on plaque psoriasis in patients also treated with
calcipotriol. Methods. The study included 60 patients divided into two
groups. The first group included patients treated with mineral waters,
peloids and calcipotriol in the Rusanda Spa, while the second one included
those treated only with calcipotriol. The study took 21 days, and each
patient was followed up for at least one month after ending the treatment.
The treatment efficacy was measured by psoriasis area severity index (PASI)
scores on the days 0, 7, 14 and 21 during the treatment and 30 after the end
of the therapy. Results. After a 3-week treatment in the Rusanda Spa, the
first group showed a decrease in PASI score by 59.45%, whereas in the group
of outpatients treated by calcipotriol it was 39.34%. On the day 30 following
the treatment, the first group presented with the PASI score reduction of
58.44%, and the second group of 34.78%. The therapeutic efficacy of mineral
waters and peloids combined with calcipotriol showed to be significantly
higher in regard to monotherapy with calcipotriol (p < 0.05). In regard to
clinical symptoms, the best results were obtained in the reduction of
desquamation (p < 0.001). Conclusion. The results of our study show that in
the treatment of plaque-type psoriasis, topical calcipotriol combined with
Spa Rusanda balneotherapy is more effective than topical calcipotriol alone.
Randomized controlled trials are needed to confirm the effects of
balneotherapy as monotherapy in treatment of this type of psoriasis. |
| format | Article |
| id | doaj-art-68121b80ebe54475aa0256185baa1ad7 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-68121b80ebe54475aa0256185baa1ad72025-08-20T02:23:51ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202015-01-0172111010101710.2298/VSP130309095G0042-84501500095GEffects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasisGolušin Zoran0Jovanović Marina1Magda Nataša2Stojanović Slobodan3Matić Milan4Petrović Aleksandra5Clinical Center of Vojvodina, Clinic of Dermatovenereology Diseases, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Clinic of Dermatovenereology Diseases, Novi Sad + Faculty of Medicine, Novi SadSpecial Hospital for Physical Medicine and Rehabilitation “Rusanda”, Melenci, SerbiaClinical Center of Vojvodina, Clinic of Dermatovenereology Diseases, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Clinic of Dermatovenereology Diseases, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Clinic of Dermatovenereology Diseases, Novi Sad + Faculty of Medicine, Novi SadBackground/Aim. Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue), balneotherapy is drawing increased attention worldwide. Being part of climatotherapy, balneotherapy is defined as the use of natural environmental factors in the treatment of health conditions, whereas in the treatment of psoriasis it means the use of mineral baths and peloids. The aim of this study was to examine the therapeutic efficacy of mineral waters and peloids of the Rusanda Spa on plaque psoriasis in patients also treated with calcipotriol. Methods. The study included 60 patients divided into two groups. The first group included patients treated with mineral waters, peloids and calcipotriol in the Rusanda Spa, while the second one included those treated only with calcipotriol. The study took 21 days, and each patient was followed up for at least one month after ending the treatment. The treatment efficacy was measured by psoriasis area severity index (PASI) scores on the days 0, 7, 14 and 21 during the treatment and 30 after the end of the therapy. Results. After a 3-week treatment in the Rusanda Spa, the first group showed a decrease in PASI score by 59.45%, whereas in the group of outpatients treated by calcipotriol it was 39.34%. On the day 30 following the treatment, the first group presented with the PASI score reduction of 58.44%, and the second group of 34.78%. The therapeutic efficacy of mineral waters and peloids combined with calcipotriol showed to be significantly higher in regard to monotherapy with calcipotriol (p < 0.05). In regard to clinical symptoms, the best results were obtained in the reduction of desquamation (p < 0.001). Conclusion. The results of our study show that in the treatment of plaque-type psoriasis, topical calcipotriol combined with Spa Rusanda balneotherapy is more effective than topical calcipotriol alone. Randomized controlled trials are needed to confirm the effects of balneotherapy as monotherapy in treatment of this type of psoriasis.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500095G.pdfpsoriasismud therapybathsSerbiavitamin Dadministration, topicaltreatment outcome |
| spellingShingle | Golušin Zoran Jovanović Marina Magda Nataša Stojanović Slobodan Matić Milan Petrović Aleksandra Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis Vojnosanitetski Pregled psoriasis mud therapy baths Serbia vitamin D administration, topical treatment outcome |
| title | Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis |
| title_full | Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis |
| title_fullStr | Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis |
| title_full_unstemmed | Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis |
| title_short | Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis |
| title_sort | effects of rusanda spa balneotherapy combined with calcipotriol on plaque psoriasis |
| topic | psoriasis mud therapy baths Serbia vitamin D administration, topical treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500095G.pdf |
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