Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation
Introduction. Benign recurrent intrahepatic cholestasis is a rare hepatologic disorder characterized by recurrent, self-limited episodes of severe pruritus, jaundice, and elevated bile acids. While there are guidelines for the management of intrahepatic cholestasis of pregnancy, the literature regar...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2021/5086846 |
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| author | Mariam Ayyash Nicolina Smith Madhurima Keerthy Ashina Singh Majid Shaman |
| author_facet | Mariam Ayyash Nicolina Smith Madhurima Keerthy Ashina Singh Majid Shaman |
| author_sort | Mariam Ayyash |
| collection | DOAJ |
| description | Introduction. Benign recurrent intrahepatic cholestasis is a rare hepatologic disorder characterized by recurrent, self-limited episodes of severe pruritus, jaundice, and elevated bile acids. While there are guidelines for the management of intrahepatic cholestasis of pregnancy, the literature regarding benign recurrent intrahepatic cholestasis and pregnancy is limited. Case. A 29-year-old G1P0 woman, with history of liver toxicity, had elevated total serum bile acid levels and liver enzymes documented at 8 weeks of gestation and throughout her pregnancy. She had a reactive nonstress test just 3 days prior to her induction. Fetal demise was noted when she presented at 36 weeks for her induction. Conclusion. We recommend that women with elevated total serum bile acid early in pregnancy due to a separate entity relative to intrahepatic cholestasis of pregnancy be managed in a more individualized approach. |
| format | Article |
| id | doaj-art-680aa4a8f5494039b326870b959addbc |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-680aa4a8f5494039b326870b959addbc2025-08-20T03:33:54ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922021-01-01202110.1155/2021/50868465086846Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of GestationMariam Ayyash0Nicolina Smith1Madhurima Keerthy2Ashina Singh3Majid Shaman4Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USADepartment of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USADepartment of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USADepartment of Gastroenterology and Hepatology, Henry Ford Health System, Detroit, Michigan, USADivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USAIntroduction. Benign recurrent intrahepatic cholestasis is a rare hepatologic disorder characterized by recurrent, self-limited episodes of severe pruritus, jaundice, and elevated bile acids. While there are guidelines for the management of intrahepatic cholestasis of pregnancy, the literature regarding benign recurrent intrahepatic cholestasis and pregnancy is limited. Case. A 29-year-old G1P0 woman, with history of liver toxicity, had elevated total serum bile acid levels and liver enzymes documented at 8 weeks of gestation and throughout her pregnancy. She had a reactive nonstress test just 3 days prior to her induction. Fetal demise was noted when she presented at 36 weeks for her induction. Conclusion. We recommend that women with elevated total serum bile acid early in pregnancy due to a separate entity relative to intrahepatic cholestasis of pregnancy be managed in a more individualized approach.http://dx.doi.org/10.1155/2021/5086846 |
| spellingShingle | Mariam Ayyash Nicolina Smith Madhurima Keerthy Ashina Singh Majid Shaman Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation Case Reports in Obstetrics and Gynecology |
| title | Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation |
| title_full | Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation |
| title_fullStr | Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation |
| title_full_unstemmed | Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation |
| title_short | Benign Recurrent Intrahepatic Cholestasis in Pregnancy: Fetal Death at 36 Weeks of Gestation |
| title_sort | benign recurrent intrahepatic cholestasis in pregnancy fetal death at 36 weeks of gestation |
| url | http://dx.doi.org/10.1155/2021/5086846 |
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