Artery segmentation and atherosclerotic plaque quantification using AI for murine whole slide images stained with oil red O

Artery segmentation and atherosclerotic plaque quantification using AI for murine whole slide images stained with oil red O

Abstract Atherosclerosis is the leading cause of death in Western industrial nations. To study the etiology of plaque progression, atherosclerotic mouse models are widely used. Traditionally, analyzing the obtained histological whole slide images of Oil Red O-stained aortic roots required manual seg...

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Bibliographic Details
Main Authors: Johann Christopher Engster, Tobias Reinberger, Nele Blum, Pascal Stagge, Thorsten M. Buzug, Zouhair Aherrahrou, Maik Stille
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Artery segmentation
Ensemble
Machine learning
Oil red O
Plaque segmentation
Online Access:https://doi.org/10.1038/s41598-025-93967-6
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