DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos

Abstract In the germ line and during early embryogenesis, DNA methylation (DNAme) undergoes global erasure and re-establishment to support germ cell and embryonic development. While DNAme acquisition during male germ cell development is essential for setting genomic DNA methylation imprints, other i...

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Main Authors: Grigorios Fanourgakis, Laura Gaspa-Toneu, Pavel A. Komarov, Panagiotis Papasaikas, Evgeniy A. Ozonov, Sebastien A. Smallwood, Antoine H. F. M. Peters
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55441-1
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