Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group
Abstract Background Pediatric kidney transplantation is unique when compared to adults. They need optimum post-transplant care to achieve longer graft and patient survival. Infections, rejection, recurrence, malignancy, bone problems, hypertension, and surgical complications are the most important c...
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2024-10-01
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| Online Access: | https://doi.org/10.1186/s43054-024-00321-y |
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| author | Bahia Moustafa Neveen A. Soliman Ihab Shaheen Ahmed Badr Fatma M. Atia Mohamed K. El Hatw Engy Adel Mogahed Mona EL-Ghamrawy Khaled El Khashab Noha Shaheen Mohamad G. Shouman Abeer Selim Magdy El-Sharkawy Tarek Abd El Azeem Mohamad Esmat Manal Salman Bedeir Ali-El-Dein Mona Abdel Rahim Muhamed A. El-Hadedy Moatasem Elsayed Ghoneim Mai S. Korkor Tarek E. I. Omar Yasser Amer Ashraf Abdel Baky On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee |
| author_facet | Bahia Moustafa Neveen A. Soliman Ihab Shaheen Ahmed Badr Fatma M. Atia Mohamed K. El Hatw Engy Adel Mogahed Mona EL-Ghamrawy Khaled El Khashab Noha Shaheen Mohamad G. Shouman Abeer Selim Magdy El-Sharkawy Tarek Abd El Azeem Mohamad Esmat Manal Salman Bedeir Ali-El-Dein Mona Abdel Rahim Muhamed A. El-Hadedy Moatasem Elsayed Ghoneim Mai S. Korkor Tarek E. I. Omar Yasser Amer Ashraf Abdel Baky On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee |
| author_sort | Bahia Moustafa |
| collection | DOAJ |
| description | Abstract Background Pediatric kidney transplantation is unique when compared to adults. They need optimum post-transplant care to achieve longer graft and patient survival. Infections, rejection, recurrence, malignancy, bone problems, hypertension, and surgical complications are the most important challenges that require prevention, early detection, and management. Chronic allograft nephropathy needs different approaches based on its related causes, allograft pathology, graft function, and availability of re-transplantation. Aim/objectives This national adapted guideline aims to frame evidence-based post-transplant recommendations adopted or adapted from EB source guidelines to optimize post-transplant patient care. Methods Our guideline is evidence based adapted from four national and international source guidelines with permissions [KDIGO 2020, RA/BTS 2022–2018, EAU 2018] that were appraised with AGREE II instrument tool. We followed the “adapted ADAPTE” CPG formal adaptation methodology that consists of 3 phases and 24 steps and tools. Virtual monthly meetings all through the year 2023 were activated for reviewing and validation of final adaptation of evidence-based guideline draft, considering all comments of external reviewers. This guideline was registered in the practice guideline registration for transparency (PREPARE), number: PREPARE-2023CN364. Results Recommendation statements in guidelines stand for results in articles. Discussion of important recommendations and the rationale behind selection of adopted statements and tailoring of others to suit our local facilities, expertise, and renal native disease profile was presented in the text with reasons and references. Conclusion The provided guidelines aim to improve graft and patient outcome through prevention and early management of complications and suggest research areas lacking validated research recommendations. |
| format | Article |
| id | doaj-art-67fcc01f830c402d994d7da723758f31 |
| institution | OA Journals |
| issn | 2090-9942 |
| language | English |
| publishDate | 2024-10-01 |
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| series | Egyptian Pediatric Association Gazette |
| spelling | doaj-art-67fcc01f830c402d994d7da723758f312025-08-20T02:18:15ZengSpringerOpenEgyptian Pediatric Association Gazette2090-99422024-10-0172112110.1186/s43054-024-00321-yEgyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology GroupBahia Moustafa0Neveen A. Soliman1Ihab Shaheen2Ahmed Badr3Fatma M. Atia4Mohamed K. El Hatw5Engy Adel Mogahed6Mona EL-Ghamrawy7Khaled El Khashab8Noha Shaheen9Mohamad G. Shouman10Abeer Selim11Magdy El-Sharkawy12Tarek Abd El Azeem13Mohamad Esmat14Manal Salman15Bedeir Ali-El-Dein16Mona Abdel Rahim17Muhamed A. El-Hadedy18Moatasem Elsayed Ghoneim19Mai S. Korkor20Tarek E. I. Omar21Yasser Amer22Ashraf Abdel Baky23On Behalf of Egyptian Pediatric Clinical Practice Guideline CommitteePediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Nephrology, Dialysis, and Transplantation Division, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Hepatology, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Hematology, Department of Pediatric, Faculty of Medicine, Cairo UniversityPediatric Endocrinology, Department of Pediatric, Faculty of Medicine, Cairo UniversityDepartment of Clinical Pathology, Faculty of Medicine, Cairo UniversityDepartment of Pediatric, Medical Research and Clinical Studies Institute, National Research CentreDepartment of Pediatric, Medical Research and Clinical Studies Institute, National Research CentreDepartment of Internal Medicine, Nephrology and Transplantation, Faculty of Medicine, Ain Shams UniversityDepartment of Vascular Surgery, Faculty of Medicine, Ain Shams UniversityDepartment of Urology, Faculty of Medicine, Ain Shams UniversityDepartment of Pathology, Faculty of Medicine, Ain Shams UniversityMansoura Urology and Nephrology, Department of Urology, Transplantation Center, Mansoura UniversityMansoura Urology and Nephrology, Department of Pathology, Transplantation Center, Mansoura UniversityMansoura Urology and Nephrology, Department of Adult Nephrology, Transplantation Center, Mansoura UniversityMansoura Urology and Nephrology, Department of Adult Nephrology, Transplantation Center, Mansoura UniversityPediatric Nephrology Division, Department of Pediatric, Faculty of Medicine, Mansoura UniversityDepartment of Pediatrics, Faculty of Medicine, Alexandria Center for Evidence-Based Clinical Practice Guidelines, , Alexandria UniversityDepartment of Pediatrics, Faculty of Medicine, Alexandria Center for Evidence-Based Clinical Practice Guidelines, , Alexandria UniversityPediatric Allergy, Immunology and Rheumatology Unit, Department of Pediatrics, Faculty of Medicine, Ain Shams UniversityAbstract Background Pediatric kidney transplantation is unique when compared to adults. They need optimum post-transplant care to achieve longer graft and patient survival. Infections, rejection, recurrence, malignancy, bone problems, hypertension, and surgical complications are the most important challenges that require prevention, early detection, and management. Chronic allograft nephropathy needs different approaches based on its related causes, allograft pathology, graft function, and availability of re-transplantation. Aim/objectives This national adapted guideline aims to frame evidence-based post-transplant recommendations adopted or adapted from EB source guidelines to optimize post-transplant patient care. Methods Our guideline is evidence based adapted from four national and international source guidelines with permissions [KDIGO 2020, RA/BTS 2022–2018, EAU 2018] that were appraised with AGREE II instrument tool. We followed the “adapted ADAPTE” CPG formal adaptation methodology that consists of 3 phases and 24 steps and tools. Virtual monthly meetings all through the year 2023 were activated for reviewing and validation of final adaptation of evidence-based guideline draft, considering all comments of external reviewers. This guideline was registered in the practice guideline registration for transparency (PREPARE), number: PREPARE-2023CN364. Results Recommendation statements in guidelines stand for results in articles. Discussion of important recommendations and the rationale behind selection of adopted statements and tailoring of others to suit our local facilities, expertise, and renal native disease profile was presented in the text with reasons and references. Conclusion The provided guidelines aim to improve graft and patient outcome through prevention and early management of complications and suggest research areas lacking validated research recommendations.https://doi.org/10.1186/s43054-024-00321-yPediatric kidney transplantationPost-transplant follow-up |
| spellingShingle | Bahia Moustafa Neveen A. Soliman Ihab Shaheen Ahmed Badr Fatma M. Atia Mohamed K. El Hatw Engy Adel Mogahed Mona EL-Ghamrawy Khaled El Khashab Noha Shaheen Mohamad G. Shouman Abeer Selim Magdy El-Sharkawy Tarek Abd El Azeem Mohamad Esmat Manal Salman Bedeir Ali-El-Dein Mona Abdel Rahim Muhamed A. El-Hadedy Moatasem Elsayed Ghoneim Mai S. Korkor Tarek E. I. Omar Yasser Amer Ashraf Abdel Baky On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group Egyptian Pediatric Association Gazette Pediatric kidney transplantation Post-transplant follow-up |
| title | Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group |
| title_full | Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group |
| title_fullStr | Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group |
| title_full_unstemmed | Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group |
| title_short | Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) Nephrology Group |
| title_sort | egyptian pediatric kidney transplantation highlights on post transplant follow up and management of complications by the egyptian pediatric clinical practice guidelines committee epg nephrology group |
| topic | Pediatric kidney transplantation Post-transplant follow-up |
| url | https://doi.org/10.1186/s43054-024-00321-y |
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