Functional condition of inspiratory muscles in obstructive sleep apnea patients

Background — Recurrent upper airway obstruction during the sleep is a key feature of obstructive sleep apnea (OSA). In patients with OSA, an intermittent upper airway obstruction yields an increase in inspiratory effort and, consequently, an augmented impact on inspiratory muscles (IM). However, the...

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Main Authors: Anastasia I. Miroshnichenko, Adel K. Kunarbaeva, Konstantin M. Ivanov, Igor V. Miroshnichenko, Evgeniy E. Achkasov, Sergey A. Bondarev, Eduard N. Bezuglov, Alexey A. Popov, Leonid A. Gridin, Dmitry Yu. Butko
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2022-03-01
Series:Russian Open Medical Journal
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Online Access:https://romj.org/node/445
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author Anastasia I. Miroshnichenko
Adel K. Kunarbaeva
Konstantin M. Ivanov
Igor V. Miroshnichenko
Evgeniy E. Achkasov
Sergey A. Bondarev
Eduard N. Bezuglov
Alexey A. Popov
Leonid A. Gridin
Dmitry Yu. Butko
author_facet Anastasia I. Miroshnichenko
Adel K. Kunarbaeva
Konstantin M. Ivanov
Igor V. Miroshnichenko
Evgeniy E. Achkasov
Sergey A. Bondarev
Eduard N. Bezuglov
Alexey A. Popov
Leonid A. Gridin
Dmitry Yu. Butko
author_sort Anastasia I. Miroshnichenko
collection DOAJ
description Background — Recurrent upper airway obstruction during the sleep is a key feature of obstructive sleep apnea (OSA). In patients with OSA, an intermittent upper airway obstruction yields an increase in inspiratory effort and, consequently, an augmented impact on inspiratory muscles (IM). However, the issue of IM fatigue development in OSA patients is still controversial. Objective — to investigate the functional condition of IM in patients with OSA of various degrees of severity. Material and Methods — Were examined 82 men (30-65 years old), who were distributed among four groups depending on the OSA severity. Cardiorespiratory monitoring was performed to detect OSA. IM electrical activity was detected via surface electromyography (EMG) while holding the breath (during the inhalation). Results — In the course of our study, we detected a reduction in the frequency of EMG of accessory IM, specifically sternocleidomastoid muscle (SCMM) and external intercostal muscles (EIM), accompanied by a simultaneous increase in the amplitude of EMG of SCMM, EIM, and diaphragm (D), while holding the breath (during the inhalation), in the group of patients without OSA. In patients with mild OSA, when holding the breath during the inhalation, the frequency of EMG of SCMM and EIM decreased, while the amplitude of SCMM and EIM increased. In patients with moderate OSA, when holding the breath during the inhalation, a decrease in the frequency of SCMM EMG with a simultaneous increase in the amplitude of the EIM EMG were revealed. Same maneuver in the group of patients with severe OSA yielded no significant changes in the frequency and amplitude of EMG of respiratory muscles. Conclusion — Periodic obstruction of the upper airways with OSA leads to the development of fatigue resistance in accessory IM.
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spelling doaj-art-67f1e83376c8457ca660cbb2ff557a572025-08-20T03:07:33ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152022-03-01111e010810.15275/rusomj.2022.0108Functional condition of inspiratory muscles in obstructive sleep apnea patientsAnastasia I. MiroshnichenkoAdel K. KunarbaevaKonstantin M. IvanovIgor V. MiroshnichenkoEvgeniy E. AchkasovSergey A. BondarevEduard N. BezuglovAlexey A. PopovLeonid A. GridinDmitry Yu. ButkoBackground — Recurrent upper airway obstruction during the sleep is a key feature of obstructive sleep apnea (OSA). In patients with OSA, an intermittent upper airway obstruction yields an increase in inspiratory effort and, consequently, an augmented impact on inspiratory muscles (IM). However, the issue of IM fatigue development in OSA patients is still controversial. Objective — to investigate the functional condition of IM in patients with OSA of various degrees of severity. Material and Methods — Were examined 82 men (30-65 years old), who were distributed among four groups depending on the OSA severity. Cardiorespiratory monitoring was performed to detect OSA. IM electrical activity was detected via surface electromyography (EMG) while holding the breath (during the inhalation). Results — In the course of our study, we detected a reduction in the frequency of EMG of accessory IM, specifically sternocleidomastoid muscle (SCMM) and external intercostal muscles (EIM), accompanied by a simultaneous increase in the amplitude of EMG of SCMM, EIM, and diaphragm (D), while holding the breath (during the inhalation), in the group of patients without OSA. In patients with mild OSA, when holding the breath during the inhalation, the frequency of EMG of SCMM and EIM decreased, while the amplitude of SCMM and EIM increased. In patients with moderate OSA, when holding the breath during the inhalation, a decrease in the frequency of SCMM EMG with a simultaneous increase in the amplitude of the EIM EMG were revealed. Same maneuver in the group of patients with severe OSA yielded no significant changes in the frequency and amplitude of EMG of respiratory muscles. Conclusion — Periodic obstruction of the upper airways with OSA leads to the development of fatigue resistance in accessory IM.https://romj.org/node/445obstructive sleep apneainspiratory muscleselectromyography
spellingShingle Anastasia I. Miroshnichenko
Adel K. Kunarbaeva
Konstantin M. Ivanov
Igor V. Miroshnichenko
Evgeniy E. Achkasov
Sergey A. Bondarev
Eduard N. Bezuglov
Alexey A. Popov
Leonid A. Gridin
Dmitry Yu. Butko
Functional condition of inspiratory muscles in obstructive sleep apnea patients
Russian Open Medical Journal
obstructive sleep apnea
inspiratory muscles
electromyography
title Functional condition of inspiratory muscles in obstructive sleep apnea patients
title_full Functional condition of inspiratory muscles in obstructive sleep apnea patients
title_fullStr Functional condition of inspiratory muscles in obstructive sleep apnea patients
title_full_unstemmed Functional condition of inspiratory muscles in obstructive sleep apnea patients
title_short Functional condition of inspiratory muscles in obstructive sleep apnea patients
title_sort functional condition of inspiratory muscles in obstructive sleep apnea patients
topic obstructive sleep apnea
inspiratory muscles
electromyography
url https://romj.org/node/445
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