Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries
Aims. Our aim is to investigate, in 13 cases (delivering preterm) and 21 matched (for age, parity, and gestational age) controls (delivering at term), whether midtrimester amniotic fluid concentrations of elastase, secretory leukocyte proteinase inhibitor (SLPI), soluble intercellular adhesion molec...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2006-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/MI/2006/94381 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850158308532420608 |
|---|---|
| author | Ariadne Malamitsi-Puchner Nikolaos Vrachnis Evi Samoli Stavroula Baka George Alexandrakis Karl-Philipp Puchner Zoe Iliodromiti Demetrios Hassiakos |
| author_facet | Ariadne Malamitsi-Puchner Nikolaos Vrachnis Evi Samoli Stavroula Baka George Alexandrakis Karl-Philipp Puchner Zoe Iliodromiti Demetrios Hassiakos |
| author_sort | Ariadne Malamitsi-Puchner |
| collection | DOAJ |
| description | Aims. Our aim is to investigate, in 13 cases (delivering preterm) and 21 matched (for age, parity, and gestational age) controls (delivering at term), whether midtrimester amniotic fluid concentrations of elastase, secretory leukocyte proteinase inhibitor (SLPI), soluble intercellular adhesion molecule-1, and soluble vascular cell adhesion molecule predict asymptomatic intra-amniotic inflammation/infection and preterm labor. Results. Concentrations of all substances were not statistically different among mothers, delivering preterm or at term. SLPI concentrations significantly increased in women, going into labor without ruptured membranes, irrespective of pre- or term delivery (P<.007, P<.001, resp) and correlated with
elastase (r=0.508, P<.002). Conclusions. Midtrimester amniotic fluid SLPI concentrations significantly decrease when membrane rupture precedes pre- or full-term labor. However, none of the investigated substances predict preterm delivery. |
| format | Article |
| id | doaj-art-67eae3e2ae6246eb9938989849621c35 |
| institution | OA Journals |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-67eae3e2ae6246eb9938989849621c352025-08-20T02:23:55ZengWileyMediators of Inflammation0962-93511466-18612006-01-01200610.1155/MI/2006/9438194381Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm DeliveriesAriadne Malamitsi-Puchner0Nikolaos Vrachnis1Evi Samoli2Stavroula Baka3George Alexandrakis4Karl-Philipp Puchner5Zoe Iliodromiti6Demetrios Hassiakos7Second Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceSecond Department of Obstetrics and Gynecology, University of Athens, Athens 10682, GreeceAims. Our aim is to investigate, in 13 cases (delivering preterm) and 21 matched (for age, parity, and gestational age) controls (delivering at term), whether midtrimester amniotic fluid concentrations of elastase, secretory leukocyte proteinase inhibitor (SLPI), soluble intercellular adhesion molecule-1, and soluble vascular cell adhesion molecule predict asymptomatic intra-amniotic inflammation/infection and preterm labor. Results. Concentrations of all substances were not statistically different among mothers, delivering preterm or at term. SLPI concentrations significantly increased in women, going into labor without ruptured membranes, irrespective of pre- or term delivery (P<.007, P<.001, resp) and correlated with elastase (r=0.508, P<.002). Conclusions. Midtrimester amniotic fluid SLPI concentrations significantly decrease when membrane rupture precedes pre- or full-term labor. However, none of the investigated substances predict preterm delivery.http://dx.doi.org/10.1155/MI/2006/94381 |
| spellingShingle | Ariadne Malamitsi-Puchner Nikolaos Vrachnis Evi Samoli Stavroula Baka George Alexandrakis Karl-Philipp Puchner Zoe Iliodromiti Demetrios Hassiakos Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries Mediators of Inflammation |
| title | Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries |
| title_full | Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries |
| title_fullStr | Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries |
| title_full_unstemmed | Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries |
| title_short | Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries |
| title_sort | investigation of midtrimester amniotic fluid factors as potential predictors of term and preterm deliveries |
| url | http://dx.doi.org/10.1155/MI/2006/94381 |
| work_keys_str_mv | AT ariadnemalamitsipuchner investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT nikolaosvrachnis investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT evisamoli investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT stavroulabaka investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT georgealexandrakis investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT karlphilipppuchner investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT zoeiliodromiti investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries AT demetrioshassiakos investigationofmidtrimesteramnioticfluidfactorsaspotentialpredictorsoftermandpretermdeliveries |