LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers
The composition and enzymatic cleavage of binary linear copolymers (LCPs) composed of two different units, such as the glycans chitosan, homogalacturonan, alginate, or hyaluronan, are widely investigated by researchers from various disciplines including biomedicine, material sciences, and biotechnol...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | SoftwareX |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352711025000172 |
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| author | Margareta J. Hellmann Bruno M. Moerschbacher Stefan Cord-Landwehr |
| author_facet | Margareta J. Hellmann Bruno M. Moerschbacher Stefan Cord-Landwehr |
| author_sort | Margareta J. Hellmann |
| collection | DOAJ |
| description | The composition and enzymatic cleavage of binary linear copolymers (LCPs) composed of two different units, such as the glycans chitosan, homogalacturonan, alginate, or hyaluronan, are widely investigated by researchers from various disciplines including biomedicine, material sciences, and biotechnology. The LCP Simulator is a user-friendly free web tool available to anyone without registration at https://lcp-simulator.anvil.app. The objective is to provide support for LCP-researchers, including those lacking experience in in silico analyses, by offering a low-threshold possibility to simulate a) the analysis of distributions of the two units within LCPs, and b) the influence of LCP properties on the composition of products after cleavage with enzymes of defined subsite specificities. |
| format | Article |
| id | doaj-art-67ea2f97ff9f4735b88a9f9b7ed59ef1 |
| institution | DOAJ |
| issn | 2352-7110 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | SoftwareX |
| spelling | doaj-art-67ea2f97ff9f4735b88a9f9b7ed59ef12025-08-20T03:12:39ZengElsevierSoftwareX2352-71102025-02-012910205010.1016/j.softx.2025.102050LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymersMargareta J. Hellmann0Bruno M. Moerschbacher1Stefan Cord-Landwehr2Corresponding author.; Institute for Biology and Biotechnology of Plants, University of Münster, Schlossplatz 8, 48143 Münster, GermanyInstitute for Biology and Biotechnology of Plants, University of Münster, Schlossplatz 8, 48143 Münster, GermanyInstitute for Biology and Biotechnology of Plants, University of Münster, Schlossplatz 8, 48143 Münster, GermanyThe composition and enzymatic cleavage of binary linear copolymers (LCPs) composed of two different units, such as the glycans chitosan, homogalacturonan, alginate, or hyaluronan, are widely investigated by researchers from various disciplines including biomedicine, material sciences, and biotechnology. The LCP Simulator is a user-friendly free web tool available to anyone without registration at https://lcp-simulator.anvil.app. The objective is to provide support for LCP-researchers, including those lacking experience in in silico analyses, by offering a low-threshold possibility to simulate a) the analysis of distributions of the two units within LCPs, and b) the influence of LCP properties on the composition of products after cleavage with enzymes of defined subsite specificities.http://www.sciencedirect.com/science/article/pii/S2352711025000172enzymatic cleavagelinear copolymerschitosanweb toolglycoside hydrolase |
| spellingShingle | Margareta J. Hellmann Bruno M. Moerschbacher Stefan Cord-Landwehr LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers SoftwareX enzymatic cleavage linear copolymers chitosan web tool glycoside hydrolase |
| title | LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| title_full | LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| title_fullStr | LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| title_full_unstemmed | LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| title_short | LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| title_sort | lcp simulator an easy to use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers |
| topic | enzymatic cleavage linear copolymers chitosan web tool glycoside hydrolase |
| url | http://www.sciencedirect.com/science/article/pii/S2352711025000172 |
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