Sex differences in toxicity and outcomes in patients with sarcoma treated in the perioperative setting at a comprehensive cancer center

Sex differences in toxicity and outcomes in patients with sarcoma treated in the perioperative setting at a comprehensive cancer center

BackgroundThere is an unmet need of personalized strategies taking into account the influence of sex on treatment. Toxicities commonly lead to dose reductions or delays, which may impact outcomes. The current retrospective study investigated the impact of sex on chemotherapy efficacy and toxicity, a...

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Main Authors: Ilaria Tortorelli, Benedetta Chiusole, Fabio Murtas, Antonella Galiano, Maital Bolshinsky, Selma Ahcene-Djaballah, Chiara De Toni, Salvatore Vizzaccaro, Marco Maruzzo, Umberto Basso, Alberto Banzato, Marina Coppola, Sara Lonardi, Vittorina Zagonel, Antonella Brunello
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
sarcoma
toxicity
outcome
sex differences
relative dose intensity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1585884/full
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