Evaluation of the association between bevacizumab concentration and clinical outcomes in patients with breast cancer brain metastasis

Evaluation of the association between bevacizumab concentration and clinical outcomes in patients with breast cancer brain metastasis

Bevacizumab is widely used in various clinical indications, but investigations into its optimal dosage for treating CNS metastases remain limited. The BEEP regimen, comprising bevacizumab, etoposide, and cisplatin, has recently demonstrated promising clinical outcomes for patients with breast cancer...

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Bibliographic Details
Main Authors: Chih-Ning Cheng, Yun-Jung Tsai, Huai-Hsuan Chiu, Tom Wei-Wu Chen, Ching-Hung Lin, Yen-Sheng Lu, Ching-Hua Kuo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Bevacizumab
Therapeutic drug monitoring
Overall survival
Liquid chromatography–mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402417421X
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