The expression and characterization of functionally active soluble CD83 by Pichia pastoris using high-density fermentation.

The expression and characterization of functionally active soluble CD83 by Pichia pastoris using high-density fermentation.

CD83 is a highly glycosylated type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. CD83 is upregulated during dendritic cell (DC) maturation, which is critical for the initiation of adaptive immune responses. The soluble isoform of CD83 (sCD83) is encoded by alternative...

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Main Authors: Yugang Guo, Rui Li, Xiaoping Song, Yongjun Zhong, Chenguang Wang, Hao Jia, Lidan Wu, Dong Wang, Fang Fang, Jiajia Ma, Wenyao Kang, Jie Sun, Zhigang Tian, Weihua Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089264&type=printable
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