Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation

This case highlights an atypical but important consideration in young males presenting with persistent gastrointestinal and/or genitourinary symptoms. Zinner syndrome (ZS) develops from embryologic maldevelopment of the distal mesonephric duct, resulting in ejaculatory duct atresia with consequent o...

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Main Authors: Lucinda Lau, Kishan S. Patel, Frank Santisi, Rebecca Germaine, Sunil Jeph
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2024/1718485
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author Lucinda Lau
Kishan S. Patel
Frank Santisi
Rebecca Germaine
Sunil Jeph
author_facet Lucinda Lau
Kishan S. Patel
Frank Santisi
Rebecca Germaine
Sunil Jeph
author_sort Lucinda Lau
collection DOAJ
description This case highlights an atypical but important consideration in young males presenting with persistent gastrointestinal and/or genitourinary symptoms. Zinner syndrome (ZS) develops from embryologic maldevelopment of the distal mesonephric duct, resulting in ejaculatory duct atresia with consequent obstruction of the seminal vesicle and concomitant ureteral bud malformation, leading to renal agenesis/dysplasia. The lack of distinct clinical symptoms makes ZS a difficult diagnosis to reach: Abdominal pain and dysuria are often mistaken for prostatitis or cystitis. However, the use of modern imaging modalities aids in establishing the diagnosis. Early identification of ZS may delay progression to infertility as the duct obstruction may not be as extensive, though further research is needed to establish this connection.
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publishDate 2024-01-01
publisher Wiley
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series Case Reports in Radiology
spelling doaj-art-67db4a44dc8a43fb8d4ae72dd84c46b92025-08-20T03:34:02ZengWileyCase Reports in Radiology2090-68702024-01-01202410.1155/2024/1718485Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital MalformationLucinda Lau0Kishan S. Patel1Frank Santisi2Rebecca Germaine3Sunil Jeph4Department of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of Public HealthDepartment of RadiologyThis case highlights an atypical but important consideration in young males presenting with persistent gastrointestinal and/or genitourinary symptoms. Zinner syndrome (ZS) develops from embryologic maldevelopment of the distal mesonephric duct, resulting in ejaculatory duct atresia with consequent obstruction of the seminal vesicle and concomitant ureteral bud malformation, leading to renal agenesis/dysplasia. The lack of distinct clinical symptoms makes ZS a difficult diagnosis to reach: Abdominal pain and dysuria are often mistaken for prostatitis or cystitis. However, the use of modern imaging modalities aids in establishing the diagnosis. Early identification of ZS may delay progression to infertility as the duct obstruction may not be as extensive, though further research is needed to establish this connection.http://dx.doi.org/10.1155/2024/1718485
spellingShingle Lucinda Lau
Kishan S. Patel
Frank Santisi
Rebecca Germaine
Sunil Jeph
Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
Case Reports in Radiology
title Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
title_full Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
title_fullStr Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
title_full_unstemmed Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
title_short Zinner Syndrome: The Diagnosis and Management of a Rare Urogenital Malformation
title_sort zinner syndrome the diagnosis and management of a rare urogenital malformation
url http://dx.doi.org/10.1155/2024/1718485
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