Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study

Introduction: Cognitive deficits represent a core symptom of schizophrenia and a principal contributor to illness disability, yet evaluating cognition in routine clinical settings is often not feasible as cognitive assessments take longer than a standard doctor's visit. Using smartphones to ass...

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Main Authors: Aishwarya Raje, Abhijit R. Rozatkar, Urvakhsh Meherwan Mehta, Ritu Shrivastava, Ameya Bondre, Manaal Amir Ahmad, Anshika Malviya, Yogendra Sen, Deepak Tugnawat, Anant Bhan, Tamonud Modak, Nabagata Das, Srilakshmi Nagendra, Erlend Lane, Juan Castillo, John A. Naslund, John Torous, Soumya Choudhary
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Schizophrenia Research: Cognition
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215001325000046
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author Aishwarya Raje
Abhijit R. Rozatkar
Urvakhsh Meherwan Mehta
Ritu Shrivastava
Ameya Bondre
Manaal Amir Ahmad
Anshika Malviya
Yogendra Sen
Deepak Tugnawat
Anant Bhan
Tamonud Modak
Nabagata Das
Srilakshmi Nagendra
Erlend Lane
Juan Castillo
John A. Naslund
John Torous
Soumya Choudhary
author_facet Aishwarya Raje
Abhijit R. Rozatkar
Urvakhsh Meherwan Mehta
Ritu Shrivastava
Ameya Bondre
Manaal Amir Ahmad
Anshika Malviya
Yogendra Sen
Deepak Tugnawat
Anant Bhan
Tamonud Modak
Nabagata Das
Srilakshmi Nagendra
Erlend Lane
Juan Castillo
John A. Naslund
John Torous
Soumya Choudhary
author_sort Aishwarya Raje
collection DOAJ
description Introduction: Cognitive deficits represent a core symptom of schizophrenia and a principal contributor to illness disability, yet evaluating cognition in routine clinical settings is often not feasible as cognitive assessments take longer than a standard doctor's visit. Using smartphones to assess cognition in schizophrenia offers the advantages of convenience in that patients can complete assessments outside of the clinic, temporality in that longitudinal trends can be identified, and contextuality in that cognitive scores can be interpreted with other measures captured by the phone (e.g. sleep). The current study aims to design a battery of cognitive assessments corresponding to the MATRICs Consensus Battery of Cognition (MCCB), in partnership with people living with schizophrenia. Methodology: Focus group discussions (FGDs) and interviews were conducted with people diagnosed with schizophrenia across three sites (Boston, Bhopal, and Bangalore) to help design, refine, and assess the proposed smartphone battery of cognitive tests on the mindLAMP app. Interviews were conducted between December 2023 and March 2024. Inductive thematic analysis was used to analyze data. Results: Participants found the app and its proposed cognitive assessments to be acceptable, helpful, and easy to use. They particularly found the gamified nature of the cognitive tests to be appealing and engaging. However, they also proposed ways to further increase engagement by including more information about each cognitive test, more visual instructions, and more information about scoring. Across all sites, there were many similarities in themes. Discussion & conclusion: People living with schizophrenia, from different sites in the US and India, appear interested in using smartphone apps to track their cognition. Thematic analysis reinforces the importance of feedback and data sharing, although this presents a challenge, given the novel nature of smartphone-based cognitive measures that have not yet been standardized or validated.
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series Schizophrenia Research: Cognition
spelling doaj-art-67d88b4706104d0a8971d96d976848d62025-02-07T04:47:40ZengElsevierSchizophrenia Research: Cognition2215-00132025-06-0140100347Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite studyAishwarya Raje0Abhijit R. Rozatkar1Urvakhsh Meherwan Mehta2Ritu Shrivastava3Ameya Bondre4Manaal Amir Ahmad5Anshika Malviya6Yogendra Sen7Deepak Tugnawat8Anant Bhan9Tamonud Modak10Nabagata Das11Srilakshmi Nagendra12Erlend Lane13Juan Castillo14John A. Naslund15John Torous16Soumya Choudhary17All India Institute of Medical Sciences, Bhopal, IndiaAll India Institute of Medical Sciences, Bhopal, IndiaNational Institute of Mental Health and Neurosciences, Bengaluru, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaSangath, Bhopal, IndiaAll India Institute of Medical Sciences, Bhopal, IndiaNational Institute of Mental Health and Neurosciences, Bengaluru, IndiaNational Institute of Mental Health and Neurosciences, Bengaluru, IndiaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, USABeth Israel Deaconess Medical Center, Harvard Medical School, Boston, USADepartment of Global Health and Social Medicine, Harvard Medical School, Boston, USABeth Israel Deaconess Medical Center, Harvard Medical School, Boston, USANational Institute of Mental Health and Neurosciences, Bengaluru, India; Corresponding author.Introduction: Cognitive deficits represent a core symptom of schizophrenia and a principal contributor to illness disability, yet evaluating cognition in routine clinical settings is often not feasible as cognitive assessments take longer than a standard doctor's visit. Using smartphones to assess cognition in schizophrenia offers the advantages of convenience in that patients can complete assessments outside of the clinic, temporality in that longitudinal trends can be identified, and contextuality in that cognitive scores can be interpreted with other measures captured by the phone (e.g. sleep). The current study aims to design a battery of cognitive assessments corresponding to the MATRICs Consensus Battery of Cognition (MCCB), in partnership with people living with schizophrenia. Methodology: Focus group discussions (FGDs) and interviews were conducted with people diagnosed with schizophrenia across three sites (Boston, Bhopal, and Bangalore) to help design, refine, and assess the proposed smartphone battery of cognitive tests on the mindLAMP app. Interviews were conducted between December 2023 and March 2024. Inductive thematic analysis was used to analyze data. Results: Participants found the app and its proposed cognitive assessments to be acceptable, helpful, and easy to use. They particularly found the gamified nature of the cognitive tests to be appealing and engaging. However, they also proposed ways to further increase engagement by including more information about each cognitive test, more visual instructions, and more information about scoring. Across all sites, there were many similarities in themes. Discussion & conclusion: People living with schizophrenia, from different sites in the US and India, appear interested in using smartphone apps to track their cognition. Thematic analysis reinforces the importance of feedback and data sharing, although this presents a challenge, given the novel nature of smartphone-based cognitive measures that have not yet been standardized or validated.http://www.sciencedirect.com/science/article/pii/S2215001325000046SchizophreniaDigital phenotypingCognitionDigital technology
spellingShingle Aishwarya Raje
Abhijit R. Rozatkar
Urvakhsh Meherwan Mehta
Ritu Shrivastava
Ameya Bondre
Manaal Amir Ahmad
Anshika Malviya
Yogendra Sen
Deepak Tugnawat
Anant Bhan
Tamonud Modak
Nabagata Das
Srilakshmi Nagendra
Erlend Lane
Juan Castillo
John A. Naslund
John Torous
Soumya Choudhary
Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
Schizophrenia Research: Cognition
Schizophrenia
Digital phenotyping
Cognition
Digital technology
title Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
title_full Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
title_fullStr Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
title_full_unstemmed Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
title_short Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study
title_sort designing smartphone based cognitive assessments for schizophrenia perspectives from a multisite study
topic Schizophrenia
Digital phenotyping
Cognition
Digital technology
url http://www.sciencedirect.com/science/article/pii/S2215001325000046
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