WGCNA and single-cell analysis reveal ferroptosis-related gene signatures for hepatocellular carcinoma prognosis and therapy
Abstract Background Hepatocellular carcinoma (HCC) is a globally serious malignant tumor with high incidence and mortality. Ferroptosis, a newly discovered form of regulated cell death, is significant in tumor initiation and growth. Herein, we performed bioinformatics analysis in order to investigat...
Saved in:
| Main Authors: | Can Peng, Fujian Yan, Mingli Xu, Yueyue Zhao, Jiaxing Sun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-03335-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Expression of Ferroptosis-Related Genes in Hepatocellular Carcinoma and Their Relationships With Prognosis
by: Li H, et al.
Published: (2025-03-01) -
Astragaloside IV represses hepatocellular carcinoma progression by modulating HMGB1-ferroptosis axis
by: Xingyang Zhao, et al.
Published: (2025-08-01) -
TMSB4X is a regulator of inflammation-associated ferroptosis, and promotes the proliferation, migration and invasion of hepatocellular carcinoma cells
by: Linlin Tang, et al.
Published: (2024-11-01) -
Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma
by: Gang Wang, et al.
Published: (2025-04-01) -
Identification of a novel ferroptosis-related gene signature in hepatocellular carcinoma: clinical significance, tumor microenvironment, drug sensitivity, and gene landscape analysis
by: Yunzhao Hu, et al.
Published: (2025-07-01)