Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo
Impetigo is a highly contagious bacterial skin infection characterized by blistering and erosions that can lead to significant discomfort and complications. The standard treatment includes topical or systemic antibiotics, but severe cases may require advanced wound management strategies. Polylactic...
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MDPI AG
2025-06-01
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| Series: | Infectious Disease Reports |
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| Online Access: | https://www.mdpi.com/2036-7449/17/3/72 |
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| author | Ana Lorena Novoa-Moreno Mario Aurelio Martinez-Jimenez Arturo Ortiz-Alvarez Natalia Sanchez-Olivo Victor Manuel Loza-Gonzalez Jose Luis Ramirez-GarciaLuna |
| author_facet | Ana Lorena Novoa-Moreno Mario Aurelio Martinez-Jimenez Arturo Ortiz-Alvarez Natalia Sanchez-Olivo Victor Manuel Loza-Gonzalez Jose Luis Ramirez-GarciaLuna |
| author_sort | Ana Lorena Novoa-Moreno |
| collection | DOAJ |
| description | Impetigo is a highly contagious bacterial skin infection characterized by blistering and erosions that can lead to significant discomfort and complications. The standard treatment includes topical or systemic antibiotics, but severe cases may require advanced wound management strategies. Polylactic acid (PLA)-based membranes have demonstrated effectiveness in enhancing wound healing, modulating inflammation, and reducing pain. <b>Clinical case:</b> We present three cases of bullous impetigo with extensive erosions, managed using PLA membranes as an adjunct to systemic antibiotics. A significant improvement was shown after 7 days of treatment of a single application, and complete resolution was achieved after 30 days. Notably, pain was resolved within 48–72 h, highlighting the analgesic and protective properties of the membrane. <b>Conclusions:</b> These findings suggest that PLA membranes provide a viable adjunct to antibiotic therapy in bullous impetigo, accelerating healing, reducing discomfort, and improving long-term skin outcomes. Given the increasing concern over antibiotic resistance and the limitations of standard wound care, bioresorbable synthetic membranes represent a promising alternative in dermatological wound management. |
| format | Article |
| id | doaj-art-67c705dd8ce64c57bdbde06d19ac5494 |
| institution | Kabale University |
| issn | 2036-7449 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Infectious Disease Reports |
| spelling | doaj-art-67c705dd8ce64c57bdbde06d19ac54942025-08-20T03:24:40ZengMDPI AGInfectious Disease Reports2036-74492025-06-011737210.3390/idr17030072Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous ImpetigoAna Lorena Novoa-Moreno0Mario Aurelio Martinez-Jimenez1Arturo Ortiz-Alvarez2Natalia Sanchez-Olivo3Victor Manuel Loza-Gonzalez4Jose Luis Ramirez-GarciaLuna5Wound Clinic of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoWound Clinic of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoInfectology Department of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoWound Clinic of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoWound Clinic of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoWound Clinic of the Regional High-Specialty Hospital “Ignacio Morones Prieto”, San Luis Potosí 78220, SLP, MexicoImpetigo is a highly contagious bacterial skin infection characterized by blistering and erosions that can lead to significant discomfort and complications. The standard treatment includes topical or systemic antibiotics, but severe cases may require advanced wound management strategies. Polylactic acid (PLA)-based membranes have demonstrated effectiveness in enhancing wound healing, modulating inflammation, and reducing pain. <b>Clinical case:</b> We present three cases of bullous impetigo with extensive erosions, managed using PLA membranes as an adjunct to systemic antibiotics. A significant improvement was shown after 7 days of treatment of a single application, and complete resolution was achieved after 30 days. Notably, pain was resolved within 48–72 h, highlighting the analgesic and protective properties of the membrane. <b>Conclusions:</b> These findings suggest that PLA membranes provide a viable adjunct to antibiotic therapy in bullous impetigo, accelerating healing, reducing discomfort, and improving long-term skin outcomes. Given the increasing concern over antibiotic resistance and the limitations of standard wound care, bioresorbable synthetic membranes represent a promising alternative in dermatological wound management.https://www.mdpi.com/2036-7449/17/3/72skin infectionsimpetigopolylactic-acid-based biomaterialswound healinglocal anti-infective agents |
| spellingShingle | Ana Lorena Novoa-Moreno Mario Aurelio Martinez-Jimenez Arturo Ortiz-Alvarez Natalia Sanchez-Olivo Victor Manuel Loza-Gonzalez Jose Luis Ramirez-GarciaLuna Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo Infectious Disease Reports skin infections impetigo polylactic-acid-based biomaterials wound healing local anti-infective agents |
| title | Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo |
| title_full | Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo |
| title_fullStr | Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo |
| title_full_unstemmed | Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo |
| title_short | Polylactic Acid Membranes, a Novel Adjunct Treatment for Bullous Impetigo |
| title_sort | polylactic acid membranes a novel adjunct treatment for bullous impetigo |
| topic | skin infections impetigo polylactic-acid-based biomaterials wound healing local anti-infective agents |
| url | https://www.mdpi.com/2036-7449/17/3/72 |
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