Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb
Introduction: According to the World Health Organization, the estimated number of malaria cases in Pakistan is about 1.5 million. Hematological variables like platelets, total leukocyte count (TLC), and hemoglobin (Hb) need to be evaluated to diagnose malaria in suspects. This study aimed to invest...
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The Journal of Infection in Developing Countries
2016-10-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/6828 |
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| author | Hira Burhan Askari Syed Hasan Syed Mansur-ul-Haque Ghazanfar Zaidi Taha Shaikh Aisha Zia |
| author_facet | Hira Burhan Askari Syed Hasan Syed Mansur-ul-Haque Ghazanfar Zaidi Taha Shaikh Aisha Zia |
| author_sort | Hira Burhan |
| collection | DOAJ |
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Introduction: According to the World Health Organization, the estimated number of malaria cases in Pakistan is about 1.5 million. Hematological variables like platelets, total leukocyte count (TLC), and hemoglobin (Hb) need to be evaluated to diagnose malaria in suspects. This study aimed to investigate the association between blood group and susceptibility to malaria and effects on platelets, TLC, and Hb. Methodology: This was a case-control study with a sample size of 446, of which 224 were malarial cases and 222 were controls. A designated questionnaire was developed to know age, gender, malarial strain, Hb, TLC, platelets, and blood group. Results: Of 224 malarial cases, 213 were P. vivax, and 11 were P. falciparum. There were 58 patients with blood group A, 72 with group B, 69 were O and 23 were AB. There was no significant difference in the blood group of controls compared to malarial patients (p > 0.05). Mean Hb level was 11.5mg/dL in malaria patients and 12.5mg/dL in controls. There was significant difference (p<0.01) in the mean platelet count in malarial (11,7000/μL) and control (24,5000/μL) patients. All blood groups showed similar falls in Hb and platelet levels, showing no significant difference among blood groups (p = 0.79 and p = 0.52, respectively). TLC was not significant between malarial and control groups (p = 0.072). Males were two times susceptible to malaria. Conclusions: There was no significant association between the type of blood group and susceptibility to malaria or developing anemia or thrombocytopenia.
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| format | Article |
| id | doaj-art-67c56a4a4e06408690fef0715ad0d291 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2016-10-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-67c56a4a4e06408690fef0715ad0d2912025-08-20T02:16:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-10-01101010.3855/jidc.6828Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and HbHira Burhan0Askari Syed Hasan1Syed Mansur-ul-Haque2Ghazanfar Zaidi3Taha Shaikh4Aisha Zia5Dow University of Health Sciences, Karachi, PakistanDow University of Health Sciences, Karachi, PakistanDow University of Health Sciences, Karachi, PakistanDow University of Health Sciences, Karachi, PakistanDow University of Health Sciences, Karachi, PakistanDow University of Health Sciences, Karachi, Pakistan Introduction: According to the World Health Organization, the estimated number of malaria cases in Pakistan is about 1.5 million. Hematological variables like platelets, total leukocyte count (TLC), and hemoglobin (Hb) need to be evaluated to diagnose malaria in suspects. This study aimed to investigate the association between blood group and susceptibility to malaria and effects on platelets, TLC, and Hb. Methodology: This was a case-control study with a sample size of 446, of which 224 were malarial cases and 222 were controls. A designated questionnaire was developed to know age, gender, malarial strain, Hb, TLC, platelets, and blood group. Results: Of 224 malarial cases, 213 were P. vivax, and 11 were P. falciparum. There were 58 patients with blood group A, 72 with group B, 69 were O and 23 were AB. There was no significant difference in the blood group of controls compared to malarial patients (p > 0.05). Mean Hb level was 11.5mg/dL in malaria patients and 12.5mg/dL in controls. There was significant difference (p<0.01) in the mean platelet count in malarial (11,7000/μL) and control (24,5000/μL) patients. All blood groups showed similar falls in Hb and platelet levels, showing no significant difference among blood groups (p = 0.79 and p = 0.52, respectively). TLC was not significant between malarial and control groups (p = 0.072). Males were two times susceptible to malaria. Conclusions: There was no significant association between the type of blood group and susceptibility to malaria or developing anemia or thrombocytopenia. https://jidc.org/index.php/journal/article/view/6828Malariahemoglobinplatelet |
| spellingShingle | Hira Burhan Askari Syed Hasan Syed Mansur-ul-Haque Ghazanfar Zaidi Taha Shaikh Aisha Zia Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb Journal of Infection in Developing Countries Malaria hemoglobin platelet |
| title | Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb |
| title_full | Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb |
| title_fullStr | Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb |
| title_full_unstemmed | Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb |
| title_short | Association between blood group and susceptibility to malaria and its effects on platelets, TLC, and Hb |
| title_sort | association between blood group and susceptibility to malaria and its effects on platelets tlc and hb |
| topic | Malaria hemoglobin platelet |
| url | https://jidc.org/index.php/journal/article/view/6828 |
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