Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age

Aim. To develop the software for the diagnosis of polycystic ovary syndrome in women of early reproductive age.Material and Methods. We consecutively recruited 200 women of early reproductive age (18-35 years) with or without polycystic ovary syndrome (100 women per group) and performed standard cli...

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Main Authors: A. Yu. Beglova, S. I. Yelgina
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2020-03-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/218
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author A. Yu. Beglova
S. I. Yelgina
author_facet A. Yu. Beglova
S. I. Yelgina
author_sort A. Yu. Beglova
collection DOAJ
description Aim. To develop the software for the diagnosis of polycystic ovary syndrome in women of early reproductive age.Material and Methods. We consecutively recruited 200 women of early reproductive age (18-35 years) with or without polycystic ovary syndrome (100 women per group) and performed standard clinical, laboratory, and ultrasound examination. In particular, we evaluated the duration of the menstrual cycle (oligo/ amenorrhea), ovarian reserve, and ultrasound parameters of the uterus and appendages (antiMullerian hormone level, ovarian volume, and antral follicle count). Anti-Mullerian hormone level was measured by means of enzyme-linked immunosorbent assay while ovarian volume and antral follicle count were examined on the 3rd day of the menstrual cycle using a transvaginal ultrasound examination.Results. We found statistically significant differences in the indicators of ovarian reserve in women of early reproductive age between the patients with and without polycystic ovary syndrome. Employing a logistic regression analysis, we developed a software for the automated diagnosis of polycystic ovary syndrome. Sensitivity and specificity of this software were 70.9% and 75.7%, respectively.The «Clinical, Laboratory, and Ultrasound Diagnostics of Polycystic Ovary Syndrome (CLOUDPOS)» software was developed and registered by Federal Intellectual Property Service (certificate No. 2019662249, date of registration 09/19/2019).Conclusion. Our software can be recommended as an accessory tool for the diagnosis of polycystic ovary syndrome.
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spelling doaj-art-67c54bc54d6843ab88aae477dec0d1782025-08-20T02:49:12ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412020-03-0151354510.23946/2500-0764-2020-5-1-35-45187Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive ageA. Yu. Beglova0S. I. Yelgina1Kemerovo State Medical UniversityKemerovo State Medical UniversityAim. To develop the software for the diagnosis of polycystic ovary syndrome in women of early reproductive age.Material and Methods. We consecutively recruited 200 women of early reproductive age (18-35 years) with or without polycystic ovary syndrome (100 women per group) and performed standard clinical, laboratory, and ultrasound examination. In particular, we evaluated the duration of the menstrual cycle (oligo/ amenorrhea), ovarian reserve, and ultrasound parameters of the uterus and appendages (antiMullerian hormone level, ovarian volume, and antral follicle count). Anti-Mullerian hormone level was measured by means of enzyme-linked immunosorbent assay while ovarian volume and antral follicle count were examined on the 3rd day of the menstrual cycle using a transvaginal ultrasound examination.Results. We found statistically significant differences in the indicators of ovarian reserve in women of early reproductive age between the patients with and without polycystic ovary syndrome. Employing a logistic regression analysis, we developed a software for the automated diagnosis of polycystic ovary syndrome. Sensitivity and specificity of this software were 70.9% and 75.7%, respectively.The «Clinical, Laboratory, and Ultrasound Diagnostics of Polycystic Ovary Syndrome (CLOUDPOS)» software was developed and registered by Federal Intellectual Property Service (certificate No. 2019662249, date of registration 09/19/2019).Conclusion. Our software can be recommended as an accessory tool for the diagnosis of polycystic ovary syndrome.https://fcm.kemsmu.ru/jour/article/view/218early reproductive agepolycystic ovary syndromediagnosticssoftware
spellingShingle A. Yu. Beglova
S. I. Yelgina
Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
Фундаментальная и клиническая медицина
early reproductive age
polycystic ovary syndrome
diagnostics
software
title Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
title_full Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
title_fullStr Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
title_full_unstemmed Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
title_short Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
title_sort development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age
topic early reproductive age
polycystic ovary syndrome
diagnostics
software
url https://fcm.kemsmu.ru/jour/article/view/218
work_keys_str_mv AT ayubeglova developmentofacomputerprogramforthediagnosisofpolycysticovarysyndromeinwomenofearlyreproductiveage
AT siyelgina developmentofacomputerprogramforthediagnosisofpolycysticovarysyndromeinwomenofearlyreproductiveage