Angiosarcoma of an Arteriovenous Fistula for Hemodialysis in a Kidney Transplant Recipient Affected by Lowe’s Syndrome

Objective/Background. To describe an uncommon, life-threatening condition such as angiosarcoma of a fistula for hemodialysis occurring in a transplant recipient affected by Lowe’s syndrome. Summary. We present the case of a 56-year-old male kidney transplant recipient affected by Lowe’s syndrome, al...

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Bibliographic Details
Main Authors: V. D’Ambrosio, P. Silvestri, F. Aureli, A. Sturniolo, G. Grandaliano, P. M. Ferraro
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2020/9734635
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Summary:Objective/Background. To describe an uncommon, life-threatening condition such as angiosarcoma of a fistula for hemodialysis occurring in a transplant recipient affected by Lowe’s syndrome. Summary. We present the case of a 56-year-old male kidney transplant recipient affected by Lowe’s syndrome, also known as oculocerebrorenal syndrome, a rare X-linked disorder characterized by congenital cataracts, hypotonia, intellectual disability, and Fanconi-like renal tubular dysfunction, who was diagnosed with angiosarcoma of a functioning arteriovenous fistula for hemodialysis. Conclusion. Angiosarcoma is a rare soft tissue tumor, and only 22 cases of angiosarcoma of arteriovenous fistulae were described so far; although a correlation between Lowe’s syndrome and a higher risk of tumor compared to the general population has not been described so far, the mechanisms of disease causation could be an interesting starting point for future studies on a possible connection between the two events.
ISSN:2090-6641
2090-665X