Challenges in advanced heart failure care in Japan: Bridging the gap in durable mechanical circulatory support utilization and heart transplantation

In Japan, the incidence of heart failure has escalated to become a major cause of morbidity and mortality. Advanced therapeutic interventions, such as heart transplantation and durable left ventricular assist devices, have become a focus of interest in recent decades. However, the unique sociocultur...

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Main Authors: Satoshi Miyashita, MD, Francisco B. Alexandrino, MD, Amanda R. Vest, MBBS, MPH, Tomohiro Fujisaki, MD, Wai Hong Wilson Tang, MD, Yasumasa Tsukamoto, MD, PhD, Koichiro Kinugawa, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JHLT Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S295013342400154X
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Summary:In Japan, the incidence of heart failure has escalated to become a major cause of morbidity and mortality. Advanced therapeutic interventions, such as heart transplantation and durable left ventricular assist devices, have become a focus of interest in recent decades. However, the unique sociocultural landscape of Japan, coupled with a historically controversial background of organ transplantation, has impeded progress in these areas. This has resulted in a notable donor shortage and the absence of a robust framework for heart transplantation. This review aims to highlight the specific challenges faced in advancing heart failure care in Japan and proposes strategic solutions to overcome these barriers.
ISSN:2950-1334