Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB
Aim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. Th...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2009-12-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5708 |
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| author | Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova |
| author_facet | Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova |
| author_sort | Alexander Sergeevich Ametov |
| collection | DOAJ |
| description | Aim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. The study included 464 patients with type 2 diabetes mellitus who poorly responded to metformin monotherapy. It was supplementedby diabeton MB. Efficiency and tolerability of combined treatment was evaluated from dynamics of glycemia and frequency of side-effects.40 patients were included in detailed comparative assessment (laboratory and instrumental, CGMS) of this monotherapy and fixed low-dose combinationof glibenclamide with metformin. Results. Results of comparison show that diabeton MB/metformin combination ensured most optimal glycemic control with a minimal risk of side effects. Conclusion. Diabeton MB/metformin combination is convenient, efficient and safe. |
| format | Article |
| id | doaj-art-67a94a81996746ccbe2c141ef7a7c764 |
| institution | DOAJ |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2009-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-67a94a81996746ccbe2c141ef7a7c7642025-08-20T03:09:01ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782009-12-01124687110.14341/2072-0351-57085666Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MBAlexander Sergeevich Ametov0Lyudmila Nikolaevna Bogdanova1Russian Medical Academy of Advanced Studies, MoscowRussian Medical Academy of Advanced Studies, MoscowAim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. The study included 464 patients with type 2 diabetes mellitus who poorly responded to metformin monotherapy. It was supplementedby diabeton MB. Efficiency and tolerability of combined treatment was evaluated from dynamics of glycemia and frequency of side-effects.40 patients were included in detailed comparative assessment (laboratory and instrumental, CGMS) of this monotherapy and fixed low-dose combinationof glibenclamide with metformin. Results. Results of comparison show that diabeton MB/metformin combination ensured most optimal glycemic control with a minimal risk of side effects. Conclusion. Diabeton MB/metformin combination is convenient, efficient and safe.https://www.dia-endojournals.ru/jour/article/view/5708type 2 diabetes mellitusdiabeton mbglycated hemoglobincontinuous glucose monitoring |
| spellingShingle | Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB Сахарный диабет type 2 diabetes mellitus diabeton mb glycated hemoglobin continuous glucose monitoring |
| title | Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_full | Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_fullStr | Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_full_unstemmed | Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_short | Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_sort | efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton mb |
| topic | type 2 diabetes mellitus diabeton mb glycated hemoglobin continuous glucose monitoring |
| url | https://www.dia-endojournals.ru/jour/article/view/5708 |
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