FORECASTING AND EXPERIMENTAL DETERMINATION OF DESTRUCTION IMPURITIES AND IN THE PHARMACEUTICAL COMPOSITION OF THE HYPOTENSIVE ACTION

FORECASTING AND EXPERIMENTAL DETERMINATION OF DESTRUCTION IMPURITIES AND IN THE PHARMACEUTICAL COMPOSITION OF THE HYPOTENSIVE ACTION

Determination results of impurities verapamil hydrochloride and lisinopril dihydrate using computer modeling and HPLC coupled with mass spectrometry (HPLC-MS) reported in this article. Prediction and calcu-lation of the thermodynamic characteristics of the substances carried by the method of RM1 and...

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Bibliographic Details
Main Authors: E. V. Kompantseva, A. V. Babyak, Y. V. Mudretsova, A. A. Glushko
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2015-09-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
destruction
verapamil
lisinopril
forecasting
hplc-ms analysis
Online Access:https://www.pharmpharm.ru/jour/article/view/3
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