Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT

One of the factors associated with increased morbidity of malignant neoplasms is environmental pollution with cancerogenic compounds including pesticides. Until recently, stable organic pollutant insecticide dichlorodiphenyltrichloroethane (DDT) was the single tool for fighting malaria carriers. Des...

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Main Authors: O. V. Morozova, A. Yu. Bukina, V. G. Popova, G. I. Khairieva, G. R. Sagitova, G. A. Belitsky, M. G. Yakubovskaya, K. I. Kirsanov, V. P. Maksimova
Format: Article
Language:Russian
Published: ABV-press 2024-10-01
Series:Успехи молекулярной онкологии
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Online Access:https://umo.abvpress.ru/jour/article/view/707
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author O. V. Morozova
A. Yu. Bukina
V. G. Popova
G. I. Khairieva
G. R. Sagitova
G. A. Belitsky
M. G. Yakubovskaya
K. I. Kirsanov
V. P. Maksimova
author_facet O. V. Morozova
A. Yu. Bukina
V. G. Popova
G. I. Khairieva
G. R. Sagitova
G. A. Belitsky
M. G. Yakubovskaya
K. I. Kirsanov
V. P. Maksimova
author_sort O. V. Morozova
collection DOAJ
description One of the factors associated with increased morbidity of malignant neoplasms is environmental pollution with cancerogenic compounds including pesticides. Until recently, stable organic pollutant insecticide dichlorodiphenyltrichloroethane (DDT) was the single tool for fighting malaria carriers. Despite vast evidence of its negative effect on human health, DDT is still used in some countries.Aim. To perform a comprehensive analysis of the dynamics of DDT pesticide use and the consequences of its use on the global healthcare as well as to investigate the mechanism of its action on the human body including the endocrine system and cancerogenic effects.The review was composed using the PubMed (2853 publications), Elsevier (3139 publications), eLibrary (784 publications) biomedical literature databases. Full-text articles were retrieved through PubMed Central (PMC), Science Direct, Research Gate, CyberLeninka electronic resources.
format Article
id doaj-art-679ed9d93fbd4dfcb441421bfeffdcba
institution Kabale University
issn 2313-805X
2413-3787
language Russian
publishDate 2024-10-01
publisher ABV-press
record_format Article
series Успехи молекулярной онкологии
spelling doaj-art-679ed9d93fbd4dfcb441421bfeffdcba2025-08-20T04:00:15ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872024-10-01113415510.17650/2313-805X-2024-11-3-41-55338Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDTO. V. Morozova0A. Yu. Bukina1V. G. Popova2G. I. Khairieva3G. R. Sagitova4G. A. Belitsky5M. G. Yakubovskaya6K. I. Kirsanov7V. P. Maksimova8N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; MIREA – Russian Technological UniversityN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaSechenov University, Ministry of Health of RussiaSechenov University, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; Peoples’ Friendship University of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaOne of the factors associated with increased morbidity of malignant neoplasms is environmental pollution with cancerogenic compounds including pesticides. Until recently, stable organic pollutant insecticide dichlorodiphenyltrichloroethane (DDT) was the single tool for fighting malaria carriers. Despite vast evidence of its negative effect on human health, DDT is still used in some countries.Aim. To perform a comprehensive analysis of the dynamics of DDT pesticide use and the consequences of its use on the global healthcare as well as to investigate the mechanism of its action on the human body including the endocrine system and cancerogenic effects.The review was composed using the PubMed (2853 publications), Elsevier (3139 publications), eLibrary (784 publications) biomedical literature databases. Full-text articles were retrieved through PubMed Central (PMC), Science Direct, Research Gate, CyberLeninka electronic resources.https://umo.abvpress.ru/jour/article/view/707dichlorodiphenyltrichloroethanedichlorodiphenyldichloroethyleneddtddeendocrine disruptorcarcinogen
spellingShingle O. V. Morozova
A. Yu. Bukina
V. G. Popova
G. I. Khairieva
G. R. Sagitova
G. A. Belitsky
M. G. Yakubovskaya
K. I. Kirsanov
V. P. Maksimova
Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
Успехи молекулярной онкологии
dichlorodiphenyltrichloroethane
dichlorodiphenyldichloroethylene
ddt
dde
endocrine disruptor
carcinogen
title Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
title_full Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
title_fullStr Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
title_full_unstemmed Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
title_short Two-faced Janus: on the 150<sup>th</sup> anniversary of the discovery of DDT
title_sort two faced janus on the 150 sup th sup anniversary of the discovery of ddt
topic dichlorodiphenyltrichloroethane
dichlorodiphenyldichloroethylene
ddt
dde
endocrine disruptor
carcinogen
url https://umo.abvpress.ru/jour/article/view/707
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