KCTD10 inhibits lung cancer metastasis and angiogenesis via ubiquitin-mediated β-catenin degradation

KCTD10 inhibits lung cancer metastasis and angiogenesis via ubiquitin-mediated β-catenin degradation

Lung cancer remains a critical global health concern, characterized by the highest incidence and mortality rates among all cancers. Due to its heterogeneity and complexity, the molecular mechanism underlying lung cancer occurrence and progression needs to be further investigated. KCTD10 has been imp...

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Bibliographic Details
Main Authors: Zihao Yin, Shengwen Long, Hao Zhou, Mi Ouyang, Qinghao Wang, Jun He, Rongyu Su, Zhiwei Li, Xiaofeng Ding, Shuanglin Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
KCTD10
lung cancer metastasis
specific Kctd10 knockout
β-catenin
PD-1
M6A
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1630311/full
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