Animal models of depression

The review provides and describes in detail the main most commonly used behavioral experimental models of depression. Endophenotypes and criteria of validity of behavioral methods for evaluation of antidepressant activity in compounds are described. Modeling depression using laboratory animals allow...

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Main Authors: T. L. Garibova, V. A. Kraineva, T. A. Voronina
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2017-07-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/21
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author T. L. Garibova
V. A. Kraineva
T. A. Voronina
author_facet T. L. Garibova
V. A. Kraineva
T. A. Voronina
author_sort T. L. Garibova
collection DOAJ
description The review provides and describes in detail the main most commonly used behavioral experimental models of depression. Endophenotypes and criteria of validity of behavioral methods for evaluation of antidepressant activity in compounds are described. Modeling depression using laboratory animals allows us to understand the nature of depression in humans and to search for effective ways of treating.
format Article
id doaj-art-6786cede3e024a25b659783f2d1c1e4d
institution DOAJ
issn 2587-7836
2686-8830
language Russian
publishDate 2017-07-01
publisher LLC “Publisher OKI”
record_format Article
series Фармакокинетика и Фармакодинамика
spelling doaj-art-6786cede3e024a25b659783f2d1c1e4d2025-08-20T03:19:57ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302017-07-0103141920Animal models of depressionT. L. Garibova0V. A. Kraineva1T. A. Voronina2ФГБНУ «НИИ фармакологии имени В.В. Закусова»ФГБНУ «НИИ фармакологии имени В.В. Закусова»ФГБНУ «НИИ фармакологии имени В.В. Закусова»The review provides and describes in detail the main most commonly used behavioral experimental models of depression. Endophenotypes and criteria of validity of behavioral methods for evaluation of antidepressant activity in compounds are described. Modeling depression using laboratory animals allows us to understand the nature of depression in humans and to search for effective ways of treating.https://www.pharmacokinetica.ru/jour/article/view/21модели депрессивноподобного поведения животныхкритерии оценкиanimal models of depressionendophenotypes and criteria of validity
spellingShingle T. L. Garibova
V. A. Kraineva
T. A. Voronina
Animal models of depression
Фармакокинетика и Фармакодинамика
модели депрессивноподобного поведения животных
критерии оценки
animal models of depression
endophenotypes and criteria of validity
title Animal models of depression
title_full Animal models of depression
title_fullStr Animal models of depression
title_full_unstemmed Animal models of depression
title_short Animal models of depression
title_sort animal models of depression
topic модели депрессивноподобного поведения животных
критерии оценки
animal models of depression
endophenotypes and criteria of validity
url https://www.pharmacokinetica.ru/jour/article/view/21
work_keys_str_mv AT tlgaribova animalmodelsofdepression
AT vakraineva animalmodelsofdepression
AT tavoronina animalmodelsofdepression