Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

Abstract Background The complex pathogenesis of Alzheimer’s disease (AD) has resulted in limited current biomarkers for its classification and diagnosis, necessitating further investigation into reliable universal biomarkers or combinations. Methods In this work, we collect multiple CSF proteomics d...

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Bibliographic Details
Main Authors: Xiaosen Hou, Yunjie Qiu, Hui Li, Yan Yan, Dongxu Zhao, Simei Ji, Junjun Ni, Jun Zhang, Kefu Liu, Hong Qing, Zhenzhen Quan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Machine learning
Cerebrospinal fluid
Biomarker
Online Access:https://doi.org/10.1186/s13195-025-01789-5
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