Safranal-loaded gold nanoparticles alleviate hepatocellular carcinoma via targeting the Wnt/β-catenin pathway

Safranal-loaded gold nanoparticles alleviate hepatocellular carcinoma via targeting the Wnt/β-catenin pathway

Abstract Background The Wnt/β-catenin pathway is frequently activated in hepatocellular carcinoma (HCC); thus, it is considered a potential target for novel therapies. Safranal (SAF), a natural product, is reputed for its antitumor and antioxidant activities. Gold nanoparticles (AuNPs) exhibit uniqu...

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Bibliographic Details
Main Authors: Yara A. Samra, Al Shaima G. Abd El Salam, Amr M. Abdelghany, Mamdouh M. El-Shishtawy
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
β-catenin
Safranal
Doxorubicin
Gold nanoparticles
Online Access:https://doi.org/10.1007/s12672-025-02447-w
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