Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance
Abstract Bacteriophages (phages) reprogram host metabolism and generate phenotypic heterogeneity, yet the mechanisms and ecological implications remain poorly understood representing a major knowledge gap in microbial ecology. This review explores how phage infection alters microbial physiology, con...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-05-01
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| Series: | npj Biofilms and Microbiomes |
| Online Access: | https://doi.org/10.1038/s41522-025-00727-5 |
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| _version_ | 1849325958594560000 |
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| author | Xiaolong Liang Shuo Yang Mark Radosevich Yongfeng Wang Ning Duan Yongfeng Jia |
| author_facet | Xiaolong Liang Shuo Yang Mark Radosevich Yongfeng Wang Ning Duan Yongfeng Jia |
| author_sort | Xiaolong Liang |
| collection | DOAJ |
| description | Abstract Bacteriophages (phages) reprogram host metabolism and generate phenotypic heterogeneity, yet the mechanisms and ecological implications remain poorly understood representing a major knowledge gap in microbial ecology. This review explores how phage infection alters microbial physiology, contributes to single-cell variation, and influences population dynamics. We highlight the potential consequences of phage-driven heterogeneity for microbial community structure and biogeochemical cycling, underscoring the importance of integrating phage-host interactions into ecological and ecosystem models. |
| format | Article |
| id | doaj-art-6773cab7d24c470c97e563e9069cfb0a |
| institution | Kabale University |
| issn | 2055-5008 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Biofilms and Microbiomes |
| spelling | doaj-art-6773cab7d24c470c97e563e9069cfb0a2025-08-20T03:48:15ZengNature Portfolionpj Biofilms and Microbiomes2055-50082025-05-0111111210.1038/s41522-025-00727-5Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importanceXiaolong Liang0Shuo Yang1Mark Radosevich2Yongfeng Wang3Ning Duan4Yongfeng Jia5CAS Key Laboratory of Forest Ecology and Silviculture, Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of SciencesSchool of Life Sciences, Fudan UniversityDepartment of Biosystems Engineering and Soil Science, The University of TennesseeCAS Key Laboratory of Forest Ecology and Silviculture, Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of SciencesDepartment of Biosystems Engineering and Soil Science, The University of TennesseeCAS Key Laboratory of Forest Ecology and Silviculture, Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of SciencesAbstract Bacteriophages (phages) reprogram host metabolism and generate phenotypic heterogeneity, yet the mechanisms and ecological implications remain poorly understood representing a major knowledge gap in microbial ecology. This review explores how phage infection alters microbial physiology, contributes to single-cell variation, and influences population dynamics. We highlight the potential consequences of phage-driven heterogeneity for microbial community structure and biogeochemical cycling, underscoring the importance of integrating phage-host interactions into ecological and ecosystem models.https://doi.org/10.1038/s41522-025-00727-5 |
| spellingShingle | Xiaolong Liang Shuo Yang Mark Radosevich Yongfeng Wang Ning Duan Yongfeng Jia Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance npj Biofilms and Microbiomes |
| title | Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance |
| title_full | Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance |
| title_fullStr | Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance |
| title_full_unstemmed | Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance |
| title_short | Bacteriophage-driven microbial phenotypic heterogeneity: ecological and biogeochemical importance |
| title_sort | bacteriophage driven microbial phenotypic heterogeneity ecological and biogeochemical importance |
| url | https://doi.org/10.1038/s41522-025-00727-5 |
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