Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing

Abstract Background Proton-pump-inhibitors (PPIs) are overprescribed, posing challenges to patients and healthcare systems. In Portugal, the public National Health Service (NHS) provides universal coverage and reimburses medication regardless of prescription origin, i.e., public or private. This stu...

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Main Authors: Sónia Romano, António Teixeira Rodrigues, Carla Torre, Julian Perelman
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Health Services Research
Subjects:
Online Access:https://doi.org/10.1186/s12913-024-12033-5
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author Sónia Romano
António Teixeira Rodrigues
Carla Torre
Julian Perelman
author_facet Sónia Romano
António Teixeira Rodrigues
Carla Torre
Julian Perelman
author_sort Sónia Romano
collection DOAJ
description Abstract Background Proton-pump-inhibitors (PPIs) are overprescribed, posing challenges to patients and healthcare systems. In Portugal, the public National Health Service (NHS) provides universal coverage and reimburses medication regardless of prescription origin, i.e., public or private. This study aimed to compare PPIs outpatient prescription patterns and costs among older adults in the private and public sectors. Methods A nationwide retrospective ecological study was conducted on PPIs prescribed for older adults in Portugal from 2020–2022. Data on defined daily doses (DDDs) and prices were obtained from a national public database by healthcare sector, sex, and age group (65–74, ≥ 75 years). The market share of DDD per 1000 older adults per day and the mean price per DDD (€/DDD) for all PPIs substances were compared between the public and private sectors. Results PPIs-DDDs accounted for 5.3% of all outpatient DDDs prescribed in the private sector and 5.9% in the public sector. The private sector prescribed PPIs at a 20% higher price (0.126 €/DDD) than the public (0.106 €/DDD), with greater differences among the most expensive substances (rabeprazole, lansoprazole and esomeprazole). Omeprazole (cheapest) was mostly prescribed in the public sector. In the private sector, a similar pattern was observed among those aged ≥ 75 years, whereas esomeprazole was most prescribed for those aged 65–74 years. Conclusions Given the widespread prescription of PPIs and the associated cost, it is crucial to reinforce incentives to promote rational PPIs prescription and encourage deprescription when necessary, in both sectors. Since the NHS also reimburses medications prescribed in private units, implementing monitoring measures and financial incentives to promote responsible prescribing in this sector should also be considered.
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spelling doaj-art-6772dde60ea741fbaad89ecb0f53cc022025-01-12T12:13:00ZengBMCBMC Health Services Research1472-69632025-01-0125111010.1186/s12913-024-12033-5Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribingSónia Romano0António Teixeira Rodrigues1Carla Torre2Julian Perelman3Centre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR-IF/ANF)Centre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR-IF/ANF)Faculdade de Farmácia, Universidade de LisboaNOVA National School of Public Health, NOVA University LisbonAbstract Background Proton-pump-inhibitors (PPIs) are overprescribed, posing challenges to patients and healthcare systems. In Portugal, the public National Health Service (NHS) provides universal coverage and reimburses medication regardless of prescription origin, i.e., public or private. This study aimed to compare PPIs outpatient prescription patterns and costs among older adults in the private and public sectors. Methods A nationwide retrospective ecological study was conducted on PPIs prescribed for older adults in Portugal from 2020–2022. Data on defined daily doses (DDDs) and prices were obtained from a national public database by healthcare sector, sex, and age group (65–74, ≥ 75 years). The market share of DDD per 1000 older adults per day and the mean price per DDD (€/DDD) for all PPIs substances were compared between the public and private sectors. Results PPIs-DDDs accounted for 5.3% of all outpatient DDDs prescribed in the private sector and 5.9% in the public sector. The private sector prescribed PPIs at a 20% higher price (0.126 €/DDD) than the public (0.106 €/DDD), with greater differences among the most expensive substances (rabeprazole, lansoprazole and esomeprazole). Omeprazole (cheapest) was mostly prescribed in the public sector. In the private sector, a similar pattern was observed among those aged ≥ 75 years, whereas esomeprazole was most prescribed for those aged 65–74 years. Conclusions Given the widespread prescription of PPIs and the associated cost, it is crucial to reinforce incentives to promote rational PPIs prescription and encourage deprescription when necessary, in both sectors. Since the NHS also reimburses medications prescribed in private units, implementing monitoring measures and financial incentives to promote responsible prescribing in this sector should also be considered.https://doi.org/10.1186/s12913-024-12033-5Proton-pump inhibitorsPatternsOverprescribingRational prescribingPublicPrivate
spellingShingle Sónia Romano
António Teixeira Rodrigues
Carla Torre
Julian Perelman
Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
BMC Health Services Research
Proton-pump inhibitors
Patterns
Overprescribing
Rational prescribing
Public
Private
title Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
title_full Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
title_fullStr Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
title_full_unstemmed Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
title_short Patterns of outpatient proton‒pump inhibitors use among older adults in a duplicative health system: comparing public and private prescribing
title_sort patterns of outpatient proton pump inhibitors use among older adults in a duplicative health system comparing public and private prescribing
topic Proton-pump inhibitors
Patterns
Overprescribing
Rational prescribing
Public
Private
url https://doi.org/10.1186/s12913-024-12033-5
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