Animal-derived therapeutic alternatives for candidiasis treatment

Fungal infections are considered diseases of medical importance, and their incidence has been increasing in recent years, especially in immunocompromised and hospitalized patients. Despite the repertoire of antifungal drugs available on the pharmaceutical market, these infections cause co...

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Main Authors: Manuela Gómez-Gaviria, Joaquín O. Chávez-Santiago, José A. Martínez-Álvarez, Héctor M. Mora-Montes
Format: Article
Language:English
Published: Academia.edu Journals 2023-03-01
Series:Academia Biology
Online Access:https://www.academia.edu/98962657/Animal_derived_therapeutic_alternatives_for_candidiasis_treatment
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author Manuela Gómez-Gaviria
Joaquín O. Chávez-Santiago
José A. Martínez-Álvarez
Héctor M. Mora-Montes
author_facet Manuela Gómez-Gaviria
Joaquín O. Chávez-Santiago
José A. Martínez-Álvarez
Héctor M. Mora-Montes
author_sort Manuela Gómez-Gaviria
collection DOAJ
description Fungal infections are considered diseases of medical importance, and their incidence has been increasing in recent years, especially in immunocompromised and hospitalized patients. Despite the repertoire of antifungal drugs available on the pharmaceutical market, these infections cause considerable morbidity and mortality worldwide each year. Candida spp. are opportunistic fungi that represent a great threat to public health. These organisms frequently cause mucosal and skin infections, but in vulnerable patients can develop life-threatening systemic infections. Recently, an increase in the isolation frequency of species different from Candida albicans has been observed, and some of them are characterized by the ability to develop resistance to antifungal drugs, which could be related to the misuse of these agents and biological attributes that allow drug resistance. Thus, the search for new therapeutic options to expand the alternatives to control candidiasis and other fungal infections is a priority. This review article shows an update on the recent literature related to new prophylactic strategies derived from marine animals, insects, amphibians, and reptiles for the treatment of invasive candidiasis.
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publisher Academia.edu Journals
record_format Article
series Academia Biology
spelling doaj-art-676ede33a11b4c2f9a252893a04ba6942025-02-10T23:12:33ZengAcademia.edu JournalsAcademia Biology2837-40102023-03-011110.20935/AcadBiol6082Animal-derived therapeutic alternatives for candidiasis treatmentManuela Gómez-Gaviria0Joaquín O. Chávez-Santiago1José A. Martínez-Álvarez2Héctor M. Mora-Montes3Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, México.Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, México.Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, México.Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, México. Fungal infections are considered diseases of medical importance, and their incidence has been increasing in recent years, especially in immunocompromised and hospitalized patients. Despite the repertoire of antifungal drugs available on the pharmaceutical market, these infections cause considerable morbidity and mortality worldwide each year. Candida spp. are opportunistic fungi that represent a great threat to public health. These organisms frequently cause mucosal and skin infections, but in vulnerable patients can develop life-threatening systemic infections. Recently, an increase in the isolation frequency of species different from Candida albicans has been observed, and some of them are characterized by the ability to develop resistance to antifungal drugs, which could be related to the misuse of these agents and biological attributes that allow drug resistance. Thus, the search for new therapeutic options to expand the alternatives to control candidiasis and other fungal infections is a priority. This review article shows an update on the recent literature related to new prophylactic strategies derived from marine animals, insects, amphibians, and reptiles for the treatment of invasive candidiasis.https://www.academia.edu/98962657/Animal_derived_therapeutic_alternatives_for_candidiasis_treatment
spellingShingle Manuela Gómez-Gaviria
Joaquín O. Chávez-Santiago
José A. Martínez-Álvarez
Héctor M. Mora-Montes
Animal-derived therapeutic alternatives for candidiasis treatment
Academia Biology
title Animal-derived therapeutic alternatives for candidiasis treatment
title_full Animal-derived therapeutic alternatives for candidiasis treatment
title_fullStr Animal-derived therapeutic alternatives for candidiasis treatment
title_full_unstemmed Animal-derived therapeutic alternatives for candidiasis treatment
title_short Animal-derived therapeutic alternatives for candidiasis treatment
title_sort animal derived therapeutic alternatives for candidiasis treatment
url https://www.academia.edu/98962657/Animal_derived_therapeutic_alternatives_for_candidiasis_treatment
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AT hectormmoramontes animalderivedtherapeuticalternativesforcandidiasistreatment