Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation
Abstract Chirality evolution is ubiquitous and important in nature, but achieving it in artificial systems is still challenging. Herein, the chirality evolution of supramolecular helices based on l‐phenylalanine derivative (LPF) and naphthylamide derivate (NDIAPY) is achieved by the strategy of elec...
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| Format: | Article |
| Language: | English |
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Wiley
2025-02-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202408499 |
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| author | Laiben Gao Xiaoqiu Dou Chao Xing Kaikai Yang Changli Zhao Chuanliang Feng |
| author_facet | Laiben Gao Xiaoqiu Dou Chao Xing Kaikai Yang Changli Zhao Chuanliang Feng |
| author_sort | Laiben Gao |
| collection | DOAJ |
| description | Abstract Chirality evolution is ubiquitous and important in nature, but achieving it in artificial systems is still challenging. Herein, the chirality evolution of supramolecular helices based on l‐phenylalanine derivative (LPF) and naphthylamide derivate (NDIAPY) is achieved by the strategy of electron transfer (ET) assisted secondary nucleation. ET from LPF to NDIAPY can be triggered by 5 s UV irradiation on left‐handed LPF‐NDIAPY co‐assemblies, leading to NDIAPY radical anions and partial disassembly of the helices. Meanwhile, spontaneous reversion of radical anions into monomers occurs upon removal of UV light, and the surface of residual co‐assemblies can accelerate the reversion process. This surface accelerated reversion of ET further facilitates the secondary nucleation‐elongation events, giving rise to the formation of scale‐amplified and g vale‐increased left‐handed helices. Meanwhile, chirality evolution controlled by ET assisted secondary nucleation process can be also realized by adding the prepared LPF‐NDIAPY co‐assemblies into the total ET system. This study may provide a useful approach to constructing and modulating diverse chiral structures by manipulating the secondary nucleation process. |
| format | Article |
| id | doaj-art-676860c9da1c43b8b6e870b008afa4c8 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-676860c9da1c43b8b6e870b008afa4c82025-02-04T13:14:55ZengWileyAdvanced Science2198-38442025-02-01125n/an/a10.1002/advs.202408499Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary NucleationLaiben Gao0Xiaoqiu Dou1Chao Xing2Kaikai Yang3Changli Zhao4Chuanliang Feng5State Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaState Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaState Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaState Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaState Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaState Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong University Shanghai 200230 P. R. ChinaAbstract Chirality evolution is ubiquitous and important in nature, but achieving it in artificial systems is still challenging. Herein, the chirality evolution of supramolecular helices based on l‐phenylalanine derivative (LPF) and naphthylamide derivate (NDIAPY) is achieved by the strategy of electron transfer (ET) assisted secondary nucleation. ET from LPF to NDIAPY can be triggered by 5 s UV irradiation on left‐handed LPF‐NDIAPY co‐assemblies, leading to NDIAPY radical anions and partial disassembly of the helices. Meanwhile, spontaneous reversion of radical anions into monomers occurs upon removal of UV light, and the surface of residual co‐assemblies can accelerate the reversion process. This surface accelerated reversion of ET further facilitates the secondary nucleation‐elongation events, giving rise to the formation of scale‐amplified and g vale‐increased left‐handed helices. Meanwhile, chirality evolution controlled by ET assisted secondary nucleation process can be also realized by adding the prepared LPF‐NDIAPY co‐assemblies into the total ET system. This study may provide a useful approach to constructing and modulating diverse chiral structures by manipulating the secondary nucleation process.https://doi.org/10.1002/advs.202408499chirality evolutionelectron transferhelical nanofiberssecondary nucleationsupramolecular assembly |
| spellingShingle | Laiben Gao Xiaoqiu Dou Chao Xing Kaikai Yang Changli Zhao Chuanliang Feng Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation Advanced Science chirality evolution electron transfer helical nanofibers secondary nucleation supramolecular assembly |
| title | Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation |
| title_full | Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation |
| title_fullStr | Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation |
| title_full_unstemmed | Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation |
| title_short | Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation |
| title_sort | chirality evolution of supramolecular helices by electron transfer assisted secondary nucleation |
| topic | chirality evolution electron transfer helical nanofibers secondary nucleation supramolecular assembly |
| url | https://doi.org/10.1002/advs.202408499 |
| work_keys_str_mv | AT laibengao chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation AT xiaoqiudou chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation AT chaoxing chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation AT kaikaiyang chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation AT changlizhao chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation AT chuanliangfeng chiralityevolutionofsupramolecularhelicesbyelectrontransferassistedsecondarynucleation |